UniProt A5HC98
RNA-directed RNA polymerase L (A5HC98)
RNA-directed RNA polymerase L (UniProt A5HC98), EC 2.7.7.48, 3.1.-.-: 27 experimental structures on GenesisL1, 7 ligands bound, 205 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A5HC98
- Protein
- RNA-directed RNA polymerase L
- EC
- 2.7.7.48, 3.1.-.-
- Experimental structures
- 27
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 205 · 11 records with a druggable one
Structures
27 records of A5HC98 in the MolNFT archive: 27 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XI5 | N-terminal endonuclease domain of La Crosse virus L-protein | x-ray diffraction | A, B, C, D | — | — |
| 2XI5 | N-terminal endonuclease domain of la crosse virus L-protein | x-ray diffraction | A, B, C, D | — | — |
| 2XI7 | N-terminal endonuclease domain of La Crosse virus L-protein | x-ray diffraction | A, B, C, D | — | — |
| 2XI7 | N-terminal endonuclease domain of la crosse virus L-protein | x-ray diffraction | A, B, C, D | — | — |
| 5AMQ | Structure of the La Crosse Bunyavirus polymerase in complex with the 3' and 5' viral RNA | x-ray diffraction | A | — | — |
| 5AMQ | Structure of the la crosse bunyavirus polymerase in complex with the 3' and 5' viral RNA | x-ray diffraction | A | — | — |
| 5AMR | Structure of the La Crosse Bunyavirus polymerase in complex with the 3' viral RNA | x-ray diffraction | A | — | 20 (best 0.78) |
| 5AMR | Structure of the la crosse bunyavirus polymerase in complex with the 3' viral RNA | x-ray diffraction | A | — | — |
| 6Z6B | Structure of full-length La Crosse virus L protein (polymerase) | x-ray diffraction | EEE, PPP | ZN | 20 (best 0.81) |
| 6Z6G | Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage | electron microscopy | A | ZN, MG | 20 (best 0.82) |
| 6Z6G | Cryo-EM structure of la crosse virus polymerase at pre-initiation stage | electron microscopy | A | ZN, MG | — |
| 6Z8K | La Crosse virus polymerase at elongation mimicking stage | electron microscopy | A | ZN, MG | 20 (best 0.84) |
| 6Z8K | La crosse virus polymerase at elongation mimicking stage | electron microscopy | A | ZN, MG | — |
| 7ORI | La Crosse virus polymerase at replication late-elongation stage | electron microscopy | A | ZN, MG, POP | 20 (best 0.85) |
| 7ORI | La crosse virus polymerase at replication late-elongation stage | electron microscopy | A | ZN, MG, POP | — |
| 7ORJ | La Crosse virus polymerase at transcription capped RNA cleavage stage | electron microscopy | A | ZN, ATP | 20 (best 0.84) |
| 7ORJ | La crosse virus polymerase at transcription capped RNA cleavage stage | electron microscopy | A | GTG, ZN, ATP | — |
| 7ORK | La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase… | electron microscopy | A | MG, ZN, ATP | 20 (best 0.83) |
| 7ORK | La crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase… | electron microscopy | A | GTG, MG, ZN, ATP | — |
| 7ORL | La crosse virus polymerase at transcription initiation stage | electron microscopy | A | GTG, MG, POP, ZN | — |
| 7ORM | La Crosse virus polymerase at transcription early-elongation stage | electron microscopy | A | ZN, MG | 20 (best 0.80) |
| 7ORM | La crosse virus polymerase at transcription early-elongation stage | electron microscopy | A | ZN, MG | — |
| 7ORN | La Crosse virus polymerase at replication initiation stage | electron microscopy | A | ATP, MG | 20 (best 0.82) |
| 7ORN | La crosse virus polymerase at replication initiation stage | electron microscopy | A | ATP, MG | — |
| 7ORO | La Crosse virus polymerase at replication early-elongation stage | electron microscopy | A | ZN, MG | 20 (best 0.85) |
| 7ORO | La crosse virus polymerase at replication early-elongation stage | electron microscopy | A | ZN, MG | — |
| 7PLR | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to… | x-ray diffraction | AAA, BBB, DDD, GGG | E4Z, MN | 5 (best 0.76) |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.