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UniProt A2A259

Polycystic kidney disease 2-like 1 protein (A2A259)

Polycystic kidney disease 2-like 1 protein (UniProt A2A259): 7 experimental structures on GenesisL1, 2 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A2A259
Protein
Polycystic kidney disease 2-like 1 protein
Experimental structures
7
Predicted models
0
Ligands
2
Pockets
60 · 3 records with a druggable one

Structures

7 records of A2A259 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5Z1WCryo-EM structure of polycystic kidney disease-like channel PKD2L1electron microscopyA, B, C, DNAG20 (best 0.80)
5Z1WCryo-EM structure of polycystic kidney disease-like channel PKD2L1electron microscopyA, B, C, DNAG—
7D7EStructure of PKD1L3-CTD/PKD2L1 in apo stateelectron microscopyB, C, DNAG, CA20 (best 0.83)
7D7EStructure of PKD1L3-CTD/PKD2L1 in apo stateelectron microscopyB, C, DNAG, CA—
7D7FStructure of PKD1L3-CTD/PKD2L1 in calcium-bound stateelectron microscopyB, C, DNAG, CA20 (best 0.82)
7D7FStructure of PKD1L3-CTD/PKD2L1 in calcium-bound stateelectron microscopyB, C, DNAG, CA—
A2A259AlphaFold monomer V2.0 prediction for polycystic kidney disease 2-like 1 protein (A2A259)———

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
  • CA · Calcium ion · in 4 records

Elsewhere

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