UniProt A1ZAW0
Dicer-2, isoform A (A1ZAW0)
Dicer-2, isoform A (UniProt A1ZAW0), EC 3.1.21.1, 3.1.26.-: 19 experimental structures on GenesisL1, 2 ligands bound, 166 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A1ZAW0
- Protein
- Dicer-2, isoform A
- EC
- 3.1.21.1, 3.1.26.-, 3.1.26.3, 3.6.1.3
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 166 · 9 records with a druggable one
Structures
19 records of A1ZAW0 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BU9 | Drosophila Dicer-2 bound to blunt dsRNA | electron microscopy | A | — | 6 (best 0.77) |
| 6BU9 | Drosophila dicer-2 bound to blunt dsrna | electron microscopy | A | — | — |
| 6BUA | Drosophila dicer-2 apo homology model (helicase, platform-paz, rnaseiii domains) | electron microscopy | A | — | — |
| 7V6B | Structure of the Dicer-2-R2D2 heterodimer | electron microscopy | A | — | 20 (best 0.77) |
| 7V6B | Structure of the dicer-2-R2D2 heterodimer | electron microscopy | A | — | — |
| 7V6C | Structure of the dicer-2-R2D2 heterodimer bound to small RNA duplex | electron microscopy | A | — | — |
| 7W0A | dmDicer2-LoqsPD-dsRNA Dimer status | electron microscopy | A, E | — | 20 (best 0.84) |
| 7W0A | DMDICER2-loqspd-dsrna dimer status | electron microscopy | A, E | — | — |
| 7W0B | Dicer2-LoqsPD complex at apo status | electron microscopy | A | — | 20 (best 0.77) |
| 7W0B | DICER2-loqspd complex at apo status | electron microscopy | A | — | — |
| 7W0C | DICER2-loqs-pd-dsrna complex at early-translocation state | electron microscopy | A | ADP | — |
| 7W0D | Dicer2-LoqsPD-dsRNA complex at mid-translocation state | electron microscopy | A, F | MG, ADP | 20 (best 0.88) |
| 7W0D | DICER2-loqspd-dsrna complex at mid-translocation state | electron microscopy | A, F | MG, ADP | — |
| 7W0E | dmDicer2-LoqsPD-dsRNA Active-dicing status | electron microscopy | A | MG, ADP | 20 (best 0.81) |
| 7W0E | DMDICER2-loqspd-dsrna active-dicing status | electron microscopy | A | MG, ADP | — |
| 7W0F | dmDicer2-LoqsPD-dsRNA Post-dicing status | electron microscopy | A | — | 20 (best 0.81) |
| 7W0F | DMDICER2-loqspd-dsrna post-dicing status | electron microscopy | A | — | — |
| 8HF0 | DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state | electron microscopy | A, D | — | 20 (best 0.87) |
| 8HF1 | DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | electron microscopy | A, D, G | — | 20 (best 0.83) |
Ligands
Elsewhere
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