MolNFT v1 · #144460 · protein
Drosophila dicer-2 apo homology model (helicase, platform-paz, rnaseiii domains)
6BUA · Dicer-2, isoform a: “Drosophila dicer-2 apo homology model (helicase, platform-paz, rnaseiii domains)”. Electron microscopy, 13 pockets (best druggability 0.81). MolNFT v1 #144460 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6BUA
- Type
- protein
- Length
- 942 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dicer-2, isoform a
- EC
- 3.1.26.3, 3.6.1.3
- UniProt
- A1ZAW0
- Pockets
- 13 · best druggability 0.81
Structure
electron microscopy · 1 distinct chain · 42% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dicer-2, isoform a (EC 3.1.26.3, 3.6.1.3) | protein | 942 | 42% helix, 9% strand | A1ZAW0 |
Pockets
13 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1098 | 0.81 | 0.82 | 111 | empty |
| 2 | 1037 | 0.74 | 0.77 | 124 | empty |
| 3 | 622 | 0.70 | 0.78 | 85 | empty |
| 4 | 555 | 0.68 | 0.78 | 67 | empty |
| 5 | 546 | 0.66 | 0.77 | 62 | empty |
Compared structures
- 6BUA · Drosophila Dicer-2 apo homology model (helicase, Platform-PAZ, RNaseIII domains) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1ZAW0
- Elsewhere: RCSB PDB 6BUA · PDBe 6BUA · UniProt A1ZAW0
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