UniProt A0LU48
Depupylase (A0LU48)
Depupylase (UniProt A0LU48), EC 3.4.-.-: 14 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A0LU48
- Protein
- Depupylase
- EC
- 3.4.-.-
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 18 · 4 records with a druggable one
Structures
15 records of A0LU48 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B0R | Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway | x-ray diffraction | A | — | — |
| 4B0R | Structure of the deamidase-depupylase dop of the prokaryotic ubiquitin-like modification pathway | x-ray diffraction | A | — | — |
| 4B0S | Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway in… | x-ray diffraction | A | — | — |
| 4B0S | Structure of the deamidase-depupylase dop of the prokaryotic ubiquitin-like modification pathway in… | x-ray diffraction | A | — | — |
| 5LRT | Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway in… | x-ray diffraction | A | ADP, MG, PO4, NA | 4 (best 0.73) |
| 5LRT | Structure of the deamidase-depupylase dop of the prokaryotic ubiquitin-like modification pathway in… | x-ray diffraction | A | ADP, MG, PO4, NA | — |
| 7OXV | Crystal structure of depupylase Dop in the Dop-loop-inserted state | x-ray diffraction | A | SCN | 4 (best 0.77) |
| 7OXV | Crystal structure of depupylase dop in the dop-loop-inserted state | x-ray diffraction | A | SCN | — |
| 7OXY | Crystal structure of depupylase dop in complex with pup and AMP-pcp | x-ray diffraction | A | MG, ACP | — |
| 7OY3 | Crystal structure of depupylase Dop in complex with phosphorylated Pup and ADP | x-ray diffraction | A | K, MG, ADP | 5 (best 0.69) |
| 7OY3 | Crystal structure of depupylase dop in complex with phosphorylated pup and ADP | x-ray diffraction | A | K, MG, ADP | — |
| 7OYF | Crystal structure of depupylase dop in complex with pup and ADP/TRIFLUOROMAGNESATE | x-ray diffraction | A | MG, ADP, KQB | — |
| 7OYH | Crystal structure of depupylase Dop in complex with Pup and ADP/tetrafluoromagnesate | x-ray diffraction | A | MG, ADP, SO4, MF4 | 5 (best 0.69) |
| 7OYH | Crystal structure of depupylase dop in complex with pup and ADP/TETRAFLUOROMAGNESATE | x-ray diffraction | A | MG, ADP, SO4, MF4 | — |
| A0LU48 | AlphaFold monomer V2.0 prediction for depupylase (A0LU48) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 8 records
- ADP · Adenosine-5'-diphosphate · in 7 records
- K · Potassium ion · in 2 records
- MF4 · Tetrafluoromagnesate(2-) · in 2 records
- NA · Sodium ion · in 2 records
- PO4 · Phosphate ion · in 2 records
- SCN · Thiocyanate ion · in 2 records
- SO4 · Sulfate ion · in 2 records
- ACP · Phosphomethylphosphonic acid adenylate ester · in 1 record
- KQB · trifluoromagnesate monohydrate · in 1 record
Experiment against prediction
- 5LRT chain A against the predicted model A0LU48: TM-score 1.00, RMSD 0.34 Å
- 5LRT chain A against the predicted model A0LU48: TM-score 1.00, RMSD 0.34 Å
- 4B0R chain A against the predicted model A0LU48: TM-score 0.99, RMSD 0.59 Å
- 4B0R chain A against the predicted model A0LU48: TM-score 0.99, RMSD 0.59 Å
- 4B0S chain A against the predicted model A0LU48: TM-score 0.99, RMSD 0.71 Å
- 4B0S chain A against the predicted model A0LU48: TM-score 0.99, RMSD 0.71 Å
- 7OYF chain A against the predicted model A0LU48: TM-score 0.98, RMSD 1.10 Å
- 7OXY chain A against the predicted model A0LU48: TM-score 0.98, RMSD 1.09 Å
- 7OY3 chain A against the predicted model A0LU48: TM-score 0.98, RMSD 1.12 Å
- 7OY3 chain A against the predicted model A0LU48: TM-score 0.98, RMSD 1.12 Å
Elsewhere
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