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UniProt A0A8G2Q7Q1

2-dehydropantoate 2-reductase (A0A8G2Q7Q1)

2-dehydropantoate 2-reductase (UniProt A0A8G2Q7Q1): 5 experimental structures on GenesisL1, 4 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A8G2Q7Q1
Protein
2-dehydropantoate 2-reductase
Experimental structures
5
Predicted models
0
Ligands
4
Pockets
21 · 5 records with a druggable one

Structures

5 records of A0A8G2Q7Q1 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8IWGPseudomoans Aerugiona Wildtype Ketopantoate Reductase native structurex-ray diffractionA, B—6 (best 0.72)
8IWQPseudomoans Aerugiona Native Ketopantoate Reductase with glycerolx-ray diffractionB, A—2 (best 0.77)
8IX9Pseudomoans Aerugiona Wildtype Ketopantoate Reductase with NADPHx-ray diffractionB, A, CNDP5 (best 0.87)
8IXHPseudomoans aeruginosa Wildtype Ketopantoate Reductase With 3-Methyl-2-oxovalerate at substrate sitex-ray diffractionA, B, C1QQ4 (best 0.86)
8IXMPseudomoans Aerugiona Wildtype Ketopantoate Reductase ternary complex with NADP+ and…x-ray diffractionA, BNAP, COI4 (best 0.79)

Ligands

  • 1QQ · (3S)-3-methyl-2-oxopentanoic acid · in 1 record
  • COI · 2-oxo-4-methylpentanoic acid · in 1 record
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 1 record
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 1 record

Elsewhere

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