UniProt A0A8D0VN39
Tubulin beta chain (A0A8D0VN39)
Tubulin beta chain (UniProt A0A8D0VN39), EC 6.3.2.25: 4 experimental structures on GenesisL1, 7 ligands bound, 51 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A8D0VN39
- Protein
- Tubulin beta chain
- EC
- 6.3.2.25
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 51 · 4 records with a druggable one
Structures
4 records of A0A8D0VN39 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8WMU | Structural basis of tubulin and heterocyclic podophyllotoxins complex for anticancer agents with… | x-ray diffraction | B, D | GDP, MG, A1D55, GTP | 11 (best 0.87) |
| 8YTX | Tubulin-RB3-TTL in complex with compound SI9 | x-ray diffraction | B, D | GDP, MG, A1D68, GTP | 13 (best 0.81) |
| 8YU9 | Tubulin-RB3-TTL in complex with compound SI10 | x-ray diffraction | B, D | GTP, A1D7A, GDP, MG | 14 (best 0.87) |
| 8YUA | Tubulin-RB3-TTL in complex with compound SI10 | x-ray diffraction | B, D | GTP, GDP, MG, A1D69 | 13 (best 0.83) |
Ligands
- GDP · Guanosine-5'-diphosphate · in 4 records
- GTP · Guanosine-5'-triphosphate · in 4 records
- MG · Magnesium ion · in 4 records
- A1D55 · (5~{S},5~{a}~{S},8~{a}~{R},9~{R})-5-(quinolin-6-ylamino)-9-(3,4,5-trimethoxyphenyl)-5~{a},6,8~{a},9-tetrahydro-5~{H}-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one · in 1 record
- A1D68 · 2-chloranyl-~{N}-(4-methoxyphenyl)-~{N}-methyl-thieno[2,3-d]pyrimidin-4-amine · in 1 record
- A1D69 · 2-chloranyl-~{N}-(4-methoxyphenyl)-~{N}-methyl-thieno[3,2-d]pyrimidin-4-amine · in 1 record
- A1D7A · 4-(2-chloranylthieno[3,2-d]pyrimidin-4-yl)-7-methoxy-1,3-dihydroquinoxalin-2-one · in 1 record
Elsewhere
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