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UniProt A0A5B8RNS7

MHC class I antigen, A-2 alpha chain (A0A5B8RNS7)

MHC class I antigen, A-2 alpha chain (UniProt A0A5B8RNS7): 27 experimental structures on GenesisL1, 4 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A5B8RNS7
Protein
MHC class I antigen, A-2 alpha chain
Experimental structures
27
Predicted models
0
Ligands
4
Pockets
36 · 4 records with a druggable one

Structures

27 records of A0A5B8RNS7 in the MolNFT archive: 27 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4GKNA2-MHC Complex carrying FATGIGIITVx-ray diffractionA, D——
4GKNA2-MHC complex carrying fatgigiitvx-ray diffractionA, D——
6TMOStructure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting…x-ray diffractionASO4, TAM7 (best 0.68)
6TMOStructure determination of an enhanced affinity TCR, A24B17, in complex with HLA-A*02:01 presenting…x-ray diffractionASO4, TAM—
6TRNCrystal structure of HLA A2*01-avydgrehtvx-ray diffractionA——
6TROCrystal structure of the T-cell receptor GVY01 bound to HLA A2*01- gvydgrehtvx-ray diffractionA——
6UZ1Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with TAX/HLA-A2x-ray diffractionA, F——
6VM7SILv44 T cell receptor bound to HLA-A2 presenting gp100 peptide (ITDQVPFSV)x-ray diffractionA—6 (best 0.77)
6VM7SILV44 T cell receptor bound to HLA-A2 presenting GP100 peptide (itdqvpfsv)x-ray diffractionA——
6VM8SILV44 T cell receptor bound to HLA-A2 presenting GP100T2M peptide (imdqvpfsv)x-ray diffractionA——
6VM9T4H2 T cell receptor bound to HLA-A2 presenting GP100T2M peptide (imdqvpfsv)x-ray diffractionA——
6VMAT4H2 T cell receptor bound to HLA-A2 presenting GP100 peptide (itdqvpfsv)x-ray diffractionA——
6VMCT4H2 T cell receptor bound to HLA-A2 presenting GP100T2L peptide (ildqvpfsv)x-ray diffractionA——
6Z9VHuman class I major histocompatibility complex, A02 allele, presenting iigwmwipvx-ray diffractionA, DSO4, P4G—
6Z9XHuman class I major histocompatibility complex, A02 allele, presenting lls (T-BUTYL)Y fgtptx-ray diffractionA, DSO4—
7N1ASARS-cov-2 ylq peptide binds to HLA-A2x-ray diffractionA, D——
7N1BSARS-CoV-2 RLQ peptide binds to HLA-A2x-ray diffractionA, D—10 (best 0.76)
7N1BSARS-cov-2 rlq peptide binds to HLA-A2x-ray diffractionA, D——
7N1ESARS-cov-2 rlq peptide-specific TCR PRLQ3 binds to rlq-HLA-A2x-ray diffractionA——
7N1FSARS-cov-2 ylq peptide-specific TCR PYLQ7 binds to ylq-HLA-A2x-ray diffractionA——
7P3DMHC I A02 Allele presenting YLQPRTFLLx-ray diffractionA——
7P3DMHC I A02 allele presenting ylqprtfllx-ray diffractionA——
7P3EMHC I A02 allele presenting ylqlrtfllx-ray diffractionA, DIOD—
7PBEEmergence of immune escape at dominant SARS-cov-2 killer T-cell epitopex-ray diffractionA, FSO4—
7RE8Class I MHC (HLA-A*02) presenting alpha fetoprotein peptide (afp)x-ray diffractionA, D——
7U21Human class I MHC HLA-A2 in complex with avgsyvysv peptidex-ray diffractionA, D——
9DL1Crystal Structure of HLA-A*02:01/NY-ESO-1 (SLLMWITQV) and a target specific TRACeR-Ix-ray diffractionB, FSO413 (best 0.75)

Ligands

  • SO4 · Sulfate ion · in 6 records
  • TAM · Tris(hydroxyethyl)aminomethane · in 2 records
  • IOD · Iodide ion · in 1 record
  • P4G · 1-ethoxy-2-(2-ethoxyethoxy)ethane · in 1 record

Elsewhere

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