UniProt A0A482LRD5
Beta-lactamase (A0A482LRD5)
Beta-lactamase (UniProt A0A482LRD5), EC 3.5.2.6: 20 experimental structures on GenesisL1, 13 ligands bound, 72 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A482LRD5
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 13
- Pockets
- 72 · 10 records with a druggable one
Structures
20 records of A0A482LRD5 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PK0 | Crystal Structure of OXA-48 with Hydrolyzed Imipenem | x-ray diffraction | A, B, C, D | HIW, CL | 6 (best 0.78) |
| 6PK0 | Crystal structure of oxa-48 with hydrolyzed imipenem | x-ray diffraction | A, B, C, D | HIW, CL | — |
| 6PQI | Crystal Structure of Class D Beta-lactamase OXA-48 with Cefotaxime | x-ray diffraction | A, B, C, D | CEF, CL | 8 (best 0.81) |
| 6PQI | Crystal structure of class D beta-lactamase oxa-48 with cefotaxime | x-ray diffraction | A, B, C, D | CEF, CL | — |
| 6PSG | Crystal Structure of Class D Beta-lactamase OXA-48 with Faropenem | x-ray diffraction | A, B, C, D | CL, DGF | — |
| 6PSG | Crystal structure of class D beta-lactamase oxa-48 with faropenem | x-ray diffraction | A, B, C, D | CL, DGF | — |
| 6PT1 | Crystal Structure of Class D Beta-lactamase OXA-48 with Meropenem | x-ray diffraction | A, B, C, D | CL, MER | 10 (best 0.81) |
| 6PT1 | Crystal structure of class D beta-lactamase oxa-48 with meropenem | x-ray diffraction | A, B, C, D | CL, MER | — |
| 6PT5 | Crystal Structure of Class D Beta-lactamase OXA-48 with Cefoxitin | x-ray diffraction | A, B, C, D | CL, 1S7 | 12 (best 0.73) |
| 6PT5 | Crystal structure of class D beta-lactamase oxa-48 with cefoxitin | x-ray diffraction | A, B, C, D | CL, 1S7 | — |
| 6PTU | Crystal Structure of Class D Beta-lactamase OXA-48 with Imipenem | x-ray diffraction | A, B, C, D | CL, ID1 | 5 (best 0.79) |
| 6PTU | Crystal structure of class D beta-lactamase oxa-48 with imipenem | x-ray diffraction | A, B, C, D | CL, ID1 | — |
| 6V1O | Structure of OXA-48 bound to QPX7728 at 1.80 A | x-ray diffraction | A, B, C, D | RM9, MG, CL | 5 (best 0.82) |
| 6V1O | Structure of oxa-48 bound to QPX7728 at 1.80 a | x-ray diffraction | A, B, C, D | RM9, MG, CL | — |
| 7NRJ | Crystal Structure of a Class D carbapenemase complexed with iodide | x-ray diffraction | AAA, BBB, CCC, DDD | IOD | — |
| 7O5T | Crystal Structure of a Class D Carbapenemase Complexed with Bromide | x-ray diffraction | AAA, BBB, CCC, DDD | BR | 5 (best 0.80) |
| 7PEI | Crystal Structure of a Class D carbapenemase_E185A/R186A/R206A | x-ray diffraction | AAA, BBB | SO4 | 3 (best 0.81) |
| 7PFN | Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Imipenem | x-ray diffraction | AAA, BBB | ID1, PO4 | 4 (best 0.77) |
| 7PSE | Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Oxacillin | x-ray diffraction | AAA, BBB | CL | — |
| 7Q14 | Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Imipenem | x-ray diffraction | AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH | ID1, BR | 14 (best 0.82) |
Ligands
- CL · Chloride ion · in 15 records
- ID1 · Imipenem · in 4 records
- 1S7 · (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl) amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid · in 2 records
- BR · Bromide ion · in 2 records
- CEF · CEFOTAXIME, C3' cleaved, open, bound form · in 2 records
- DGF · (2R,5R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-[(2R)-tetrahydrofuran-2-yl]-2,5-dihydro-1,3-thiazole-4-carboxylic acid · in 2 records
- HIW · (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid · in 2 records
- MER · (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid · in 2 records
- MG · Magnesium ion · in 2 records
- RM9 · (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrocyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid · in 2 records
- IOD · Iodide ion · in 1 record
- PO4 · Phosphate ion · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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