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UniProt A0A383ZFX3

Acid ceramidase (A0A383ZFX3)

Acid ceramidase (UniProt A0A383ZFX3), EC 3.5.1.23: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
A0A383ZFX3
Protein
Acid ceramidase
EC
3.5.1.23
Experimental structures
2
Predicted models
1
Ligands
4
Pockets
7 · 1 record with a druggable one

Structures

3 records of A0A383ZFX3 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5U84Acid ceramidase (ASAH1, aCDase) from common minke whale, Cys143Ala, uncleavedx-ray diffractionA, BNAG, FUC, I3C, IOD7 (best 0.73)
5U84Acid ceramidase (ASAH1, acdase) from common minke whale, CYS143ALA, uncleavedx-ray diffractionA, BNAG, FUC, I3C, IOD—
A0A383ZFX3AlphaFold monomer V2.0 prediction for acid ceramidase (A0A383ZFX3)predicted——

Ligands

  • FUC · alpha-L-fucopyranose · in 2 records
  • I3C · 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid · in 2 records
  • IOD · Iodide ion · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records

Elsewhere

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