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UniProt A0A2J9KLI1

Isoleucine--tRNA ligase (A0A2J9KLI1)

Isoleucine--tRNA ligase (UniProt A0A2J9KLI1), EC 6.1.1.5: 6 experimental structures on GenesisL1, 6 ligands bound, 49 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A2J9KLI1
Protein
Isoleucine--tRNA ligase
EC
6.1.1.5
Experimental structures
6
Predicted models
0
Ligands
6
Pockets
49 · 6 records with a druggable one

Structures

6 records of A0A2J9KLI1 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8WNFCrystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in apo formx-ray diffractionAZN8 (best 0.74)
8WNGCrystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ilex-ray diffractionAILE, ZN8 (best 0.71)
8WNICrystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Valx-ray diffractionAZN, VAL8 (best 0.70)
8WNJCrystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ile-AMPx-ray diffractionAZN, GV67 (best 0.70)
8WO2Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Val-AMPx-ray diffractionAZN, WN98 (best 0.73)
8WO3Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Mupirocinx-ray diffractionAZN, MRC10 (best 0.69)

Ligands

  • ZN · Zinc ion · in 6 records
  • GV6 · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (2S,3S)-2-azanyl-3-methyl-pentanoate · in 1 record
  • ILE · Isoleucine · in 1 record
  • MRC · Mupirocin · in 1 record
  • VAL · Valine · in 1 record
  • WN9 · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (2S)-2-azanyl-3-methyl-butanoate · in 1 record

Elsewhere

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