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UniProt A0A100XBM0

Inosine-5'-monophosphate dehydrogenase (A0A100XBM0)

Inosine-5'-monophosphate dehydrogenase (UniProt A0A100XBM0), EC 1.1.1.205: 6 experimental structures on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A100XBM0
Protein
Inosine-5'-monophosphate dehydrogenase
EC
1.1.1.205
Experimental structures
6
Predicted models
0
Ligands
4
Pockets
2 · 2 records with a druggable one

Structures

6 records of A0A100XBM0 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5K4XM. thermoresistible IMPDH in complex with IMP and Compound 1x-ray diffractionA6Q9, IMP1 (best 0.72)
5K4XM. thermoresistible impdh in complex with imp and compound 1x-ray diffractionA6Q9, IMP—
5K4ZM. thermoresistible IMPDH in complex with IMP and Compound 6x-ray diffractionAIMP, 6Q8—
5K4ZM. thermoresistible impdh in complex with imp and compound 6x-ray diffractionAIMP, 6Q8—
6MJYM. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMPx-ray diffractionACPR1 (best 0.59)
6MJYM. thermoresistible GUAB2 delta-cbs in complex with 6CL-impx-ray diffractionACPR—

Ligands

  • IMP · Inosinic acid · in 4 records
  • 6Q8 · ~{N}-(4-fluorophenyl)-4-(2~{H}-indazol-6-ylsulfamoyl)-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide · in 2 records
  • 6Q9 · ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide · in 2 records
  • CPR · 6-chloropurine riboside, 5'-monophosphate · in 2 records

Elsewhere

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