MolNFT v1 · #156950 · protein

M. thermoresistible GUAB2 delta-cbs in complex with 6CL-imp

6MJY · Inosine-5'-monophosphate dehydrogenase: “M. thermoresistible GUAB2 delta-cbs in complex with 6CL-imp”. X-ray diffraction, 1 ligand (CPR), 1 pocket (best druggability 0.59). MolNFT v1 #156950 on GenesisL1: 3D structure, binding sites…

PDB: 6MJY
Type: protein
Length: 315 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Inosine-5'-monophosphate dehydrogenase
EC: 1.1.1.205
UniProt: A0A100XBM0
Ligands: CPR
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)	protein	315	36% helix, 19% strand	A0A100XBM0

Ligands and binding sites

CPR · 6-chloropurine riboside, 5'-monophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.59	0.77	45	CPR

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

6MJY · M. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A100XBM0
Elsewhere: RCSB PDB 6MJY · PDBe 6MJY · UniProt A0A100XBM0

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