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UniProt A0A0N9HQ36

Deoxypodophyllotoxin synthase (A0A0N9HQ36)

Deoxypodophyllotoxin synthase (UniProt A0A0N9HQ36), EC 1.14.20.8: 5 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
A0A0N9HQ36
Protein
Deoxypodophyllotoxin synthase
EC
1.14.20.8
Experimental structures
5
Predicted models
1
Ligands
4
Pockets
30 · 3 records with a druggable one

Structures

6 records of A0A0N9HQ36 in the MolNFT archive: 5 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7E37Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with…x-ray diffractionA, BFE, AKG13 (best 0.73)
7E37Crystal structure of deoxypodophyllotoxin synthase from sinopodophyllum hexandrum in complex with…x-ray diffractionA, BFE, AKG—
7E38Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with…x-ray diffractionA, BFE, YTC, YTN12 (best 0.76)
7E38Crystal structure of deoxypodophyllotoxin synthase from sinopodophyllum hexandrum in complex with…x-ray diffractionA, BFE, YTC, YTN—
8CI9Deoxypodophyllotoxin Synthase in complex with Trisx-ray diffractionCFE5 (best 0.78)
A0A0N9HQ36AlphaFold monomer V2.0 prediction for deoxypodophyllotoxin synthase (A0A0N9HQ36)predicted——

Ligands

  • FE · Fe (III) ion · in 5 records
  • AKG · 2-oxoglutaric acid · in 2 records
  • YTC · (3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one · in 2 records
  • YTN · (3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one · in 2 records

Elsewhere

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