UniProt A0A0M3KKW9
clade A/E 93TH057 HIV-1 gp120 core (A0A0M3KKW9)
clade A/E 93TH057 HIV-1 gp120 core (UniProt A0A0M3KKW9): 79 experimental structures on GenesisL1, 24 ligands bound, 162 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0M3KKW9
- Protein
- clade A/E 93TH057 HIV-1 gp120 core
- Experimental structures
- 79
- Predicted models
- 0
- Ligands
- 24
- Pockets
- 162 · 31 records with a druggable one
Structures
79 records of A0A0M3KKW9 in the MolNFT archive: 79 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DVS | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-557 | x-ray diffraction | A, B | — | — |
| 4DVS | Crystal structure of clade A/E 93TH057 HIV-1 GP120 core in complex with nbd-557 | x-ray diffraction | A, B | — | — |
| 4DVT | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AS-II-37 | x-ray diffraction | A, B | — | — |
| 4DVT | Crystal structure of clade A/E 93TH057 HIV-1 GP120 core in complex with as-II-37 | x-ray diffraction | A, B | — | — |
| 4DVV | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AS-I-261 | x-ray diffraction | A, B | — | — |
| 4DVV | Crystal structure of clade A/E 93TH057 HIV-1 GP120 core in complex with as-I-261 | x-ray diffraction | A, B | — | — |
| 4DVW | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with MAE-II-167 | x-ray diffraction | A, B | — | — |
| 4DVW | Crystal structure of clade A/E 93TH057 HIV-1 GP120 core in complex with mae-II-167 | x-ray diffraction | A, B | — | — |
| 4DVX | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with MAE-II-188 | x-ray diffraction | A, B | — | — |
| 4DVX | Crystal structure of clade A/E 93TH057 HIV-1 GP120 core in complex with mae-II-188 | x-ray diffraction | A, B | — | — |
| 5F96 | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed… | x-ray diffraction | G | NAG | 5 (best 0.65) |
| 5F96 | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4- binding site-directed… | x-ray diffraction | G | — | — |
| 5F9O | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed… | x-ray diffraction | G | NAG | — |
| 5F9O | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4- binding site-directed… | x-ray diffraction | G | — | — |
| 5F9W | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed… | x-ray diffraction | A, G | NAG, PO4 | — |
| 5F9W | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4- binding site-directed… | x-ray diffraction | A, G | — | — |
| 5FCU | Crystal structure of the inner domain of clade A/E HIV-1 GP120 in complex with the adcc-potent… | x-ray diffraction | G | NAG | — |
| 5FCU | Crystal structure of the inner domain of clade A/E HIV-1 GP120 in complex with the adcc-potent… | x-ray diffraction | G | — | — |
| 5KJR | Crystal structure of the ADCC-potent antibody N60-i3 Fab in complex with HIV-1 Clade A/E gp120… | x-ray diffraction | G | NAG | — |
| 5KJR | Crystal structure of the adcc-potent antibody N60-I3 Fab in complex with HIV-1 clade A/E GP120… | x-ray diffraction | G | NAG | — |
| 5TE6 | Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade AE… | x-ray diffraction | G | NAG | 7 (best 0.75) |
| 5TE6 | Crystal structure of broadly neutralizing VRC01-class antibody N6 in complex with HIV-1 clade ae… | x-ray diffraction | G | NAG | — |
| 5U6E | Crystal structure of clade A/E HIV-1 gp120 core in complex with NBD-14010 | x-ray diffraction | A, B | NAG, 82M | 10 (best 0.76) |
| 5U6E | Crystal structure of clade A/E HIV-1 GP120 core in complex with nbd- 14010 | x-ray diffraction | A, B | NAG, 82M | — |
| 5UEM | Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120 | x-ray diffraction | G | NAG, BMA, MAN | 6 (best 0.77) |
| 5UEM | Crystal structure of 354NC37 Fab in complex with HIV-1 clade ae strain 93TH057 GP120 | x-ray diffraction | G | NAG, MAN | — |
| 5W4L | Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with… | x-ray diffraction | G, A | NAG, CL | — |
| 5W4L | Crystal structure of the non-neutralizing and adcc-potent C11-like antibody N12-I3 in complex with… | x-ray diffraction | G, A | NAG, CL | — |
| 5WB9 | Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain… | x-ray diffraction | G | NAG | 4 (best 0.78) |
| 5WB9 | Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain… | x-ray diffraction | G | NAG | — |
| 6BCK | Crystal Structure of Broadly Neutralizing Antibody N49P7 in Complex with HIV-1 Clade AE strain… | x-ray diffraction | G | NAG | 5 (best 0.69) |
| 6BCK | Crystal structure of broadly neutralizing antibody N49P7 in complex with HIV-1 clade ae strain… | x-ray diffraction | G | NAG | — |
| 6MFP | Crystal Structure of the RV305 C1-C2 specific ADCC potent antibody DH677.3 Fab in complex with… | x-ray diffraction | G, A | NAG, CL | — |
| 6MFP | Crystal structure of the RV305 C1-C2 specific adcc potent antibody DH677.3 Fab in complex with… | x-ray diffraction | G, A | MPT, NAG, CL | — |
| 6MG7 | Crystal structure of the RV144 C1-C2 specific antibody CH54 Fab in complex with HIV-1 CLADE A/E… | x-ray diffraction | G | NAG | — |
| 6MG7 | Crystal structure of the RV144 C1-C2 specific antibody CH54 Fab in complex with HIV-1 clade A/E… | x-ray diffraction | G | MPT, NAG | — |
| 6OEJ | Crystal structure of the non-neutralizing and adcc-potent antibody C11 in complex with HIV-1 clade… | x-ray diffraction | G, A | NAG | 15 (best 0.77) |
| 6OEJ | Crystal structure of the non-neutralizing and adcc-potent antibody C11 in complex with HIV-1 clade… | x-ray diffraction | G, A | NAG | — |
| 6OFI | CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E… | x-ray diffraction | G | NAG | 6 (best 0.59) |
| 6OFI | Crystal structure of the RV144 C1-C2 specific antibody CH55 Fab in complex with HIV-1 clade A/E… | x-ray diffraction | G | NAG | — |
| 6ONE | Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-III-188-A01. | x-ray diffraction | A | NAG, MVY | 3 (best 0.53) |
| 6ONE | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-III-188-A01. | x-ray diffraction | A | NAG, MVY | — |
| 6ONF | Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-III-188-A02. | x-ray diffraction | A | NAG, MW4 | 2 (best 0.56) |
| 6ONF | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-III-188-A02. | x-ray diffraction | A | NAG, MW4 | — |
| 6ONH | Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-IV-031-A05. | x-ray diffraction | A | NAG, MWD | 2 (best 0.59) |
| 6ONH | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-031-A05. | x-ray diffraction | A | NAG, MWD | — |
| 6ONV | Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-III-027-D05. | x-ray diffraction | A | NAG, MWA | 5 (best 0.57) |
| 6ONV | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-III-027-D05. | x-ray diffraction | A | NAG, MWA | — |
| 6OOO | Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-IV-226. | x-ray diffraction | A | NAG, MXJ | 3 (best 0.55) |
| 6OOO | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-226. | x-ray diffraction | A | NAG, MXJ | — |
| 6OZ2 | Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 Clade A/E… | x-ray diffraction | G | NAG | — |
| 6OZ2 | Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 clade A/E… | x-ray diffraction | G | NAG | — |
| 6OZ3 | Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E… | x-ray diffraction | G | NAG | 8 (best 0.74) |
| 6OZ3 | Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 clade A/E… | x-ray diffraction | G | NAG | — |
| 6P9N | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-210. | x-ray diffraction | A | NAG, O51 | 3 (best 0.57) |
| 6P9N | Crystal structure of HIV-1 LM/HT clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-210. | x-ray diffraction | A | NAG, O51 | — |
| 6USW | Crystal structure of HIV-1 LM/HS clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-210 | x-ray diffraction | A | NAG, O51 | 3 (best 0.61) |
| 6USW | Crystal structure of HIV-1 LM/HS clade A/E CRF01 GP120 core in complex with (S)-mcg-IV-210 | x-ray diffraction | A | NAG, O51 | — |
| 6UT1 | Crystal structure of HIV-1 LM/HS clade A/E CRF01 GP120 core in complex with bnm-III-170 | x-ray diffraction | A | NAG, 5VG | 3 (best 0.62) |
| 6UT1 | Crystal structure of HIV-1 LM/HS clade A/E CRF01 GP120 core in complex with bnm-III-170 | x-ray diffraction | A | NAG, 5VG | — |
19 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 65 records
- CL · Chloride ion · in 8 records
- MPT · Beta-mercaptopropionic acid · in 4 records
- O51 · (3S)-N~1~-(2-aminoethyl)-N~3~-(4-chloro-3-fluorophenyl)piperidine-1,3-dicarboxamide · in 4 records
- 5VG · ~{N}'-[(1~{R},2~{R})-2-(carbamimidamidomethyl)-5-(methylaminomethyl)-2,3-dihydro-1~{H}-inden-1-yl]-~{N}-(4-chloranyl-3-fluoranyl-phenyl)ethanediamide · in 2 records
- 82M · N-{(1S)-2-amino-1-[5-(hydroxymethyl)-4-methyl-1,3-thiazol-2-yl]ethyl}-5-(4-chloro-3-fluorophenyl)-1H-pyrrole-2-carboxamide · in 2 records
- MAN · alpha-D-mannopyranose · in 2 records
- MVY · Methyl (3S)-3-[(4-chloro-3-fluorophenyl) carbamoyl]piperidine-1-carboxylate · in 2 records
- MW4 · Ethyl (3S)-3-[(4-chloro-3-fluorophenyl) carbamoyl]piperidine-1-carboxylate · in 2 records
- MWA · (3S)-N-(4-chloro-3-fluorophenyl)-1-(methylsulfonyl) piperidine-3-carboxamide · in 2 records
- MWD · (3S)-N~3~-(4-chloro-3-fluorophenyl)-N~1~-propylpiperidine-1,3-dicarboxamide · in 2 records
- MXJ · (3S,5R)-5-amino-N~3~-(4-chloro-3-fluorophenyl)-N~1~-propylpiperidine-1,3-dicarboxamide · in 2 records
- BMA · beta-D-mannopyranose · in 1 record
- MG · Magnesium ion · in 1 record
- PO4 · Phosphate ion · in 1 record
- R5K · N~1~-{(3R)-1-[2-(5-carbamimidamidopentanamido)ethyl]-1-azaspiro[5.5]undecan-3-yl}-N~2~-(4-chlorophenyl)ethanediamide · in 1 record
- YZI · (3S,5S)-5-(aminomethyl)-N-(4-chloro-3-fluorophenyl)-1-(4-methylpiperazine-1-carbonyl)piperidine-3-carboxamide · in 1 record
- Z1I · (3S,5S)-5-(aminomethyl)-N-(4-chloro-3-fluorophenyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide · in 1 record
- Z1Z · (3S,5R)-N-(4-chloro-3-fluorophenyl)-1-(4-glycylpiperazine-1-carbonyl)-5-(hydroxymethyl)piperidine-3-carboxamide · in 1 record
- Z2O · {4-[(3S,5R)-3-[(4-chloro-3-fluorophenyl)carbamoyl]-5-(hydroxymethyl)piperidine-1-carbonyl]piperazin-1-yl}acetic acid · in 1 record
- Z3F · (3S)-N-(4-chloro-3-fluorophenyl)-1-(4-methylpiperazine-1-carbonyl)piperidine-3-carboxamide · in 1 record
- Z6F · (3S,5R)-N-(4-chloro-3-fluorophenyl)-5-(hydroxymethyl)-1-(4-methylpiperazine-1-carbonyl)piperidine-3-carboxamide · in 1 record
- Z7N · (3S,5R)-N-(4-chloro-3-fluorophenyl)-5-(hydroxymethyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide · in 1 record
- ZNF · (3S)-N-(4-chloro-3-fluorophenyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide · in 1 record
Elsewhere
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