UniProt A0A0D6FWC1
Tryptophan synthase alpha chain (A0A0D6FWC1)
Tryptophan synthase alpha chain (UniProt A0A0D6FWC1), EC 4.2.1.20: 38 experimental structures on GenesisL1, 9 ligands bound, 100 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0D6FWC1
- Protein
- Tryptophan synthase alpha chain
- EC
- 4.2.1.20
- Experimental structures
- 38
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 100 · 18 records with a druggable one
Structures
38 records of A0A0D6FWC1 in the MolNFT archive: 38 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DUC | Crystal structure of mutant beta-K167T tryptophan synthase in complex with inhibitor… | x-ray diffraction | A | F9F, CL | 4 (best 0.80) |
| 6DUC | Crystal structure of mutant beta-K167T tryptophan synthase in complex with inhibitor… | x-ray diffraction | A | F9F, CL | — |
| 6O1H | Tryptophan synthase Q114A mutant in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-et… | x-ray diffraction | A | F9F, CS, CL | 5 (best 0.83) |
| 6O1H | Tryptophan synthase Q114A mutant in complex with N-(4'… | x-ray diffraction | A | F9F, CS, CL | — |
| 6VFD | Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination site and… | x-ray diffraction | A | SER, CL | 6 (best 0.66) |
| 6VFD | Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination site and… | x-ray diffraction | A | CL | — |
| 6WX3 | High resolution Tryptophan Synthase crystal structure from Salmonella typhimurium in complex with… | x-ray diffraction | A | F9F, CL, BCN | 6 (best 0.81) |
| 6WX3 | High resolution tryptophan synthase crystal structure from salmonella typhimurium in complex with… | x-ray diffraction | A | F9F, CL, BCN | — |
| 6XIN | The crystal structure of tryptophan synthase from Salmonella enterica serovar typhimurium in… | x-ray diffraction | A | CL, V41 | 5 (best 0.78) |
| 6XIN | The crystal structure of tryptophan synthase from salmonella enterica serovar typhimurium in… | x-ray diffraction | A | CL, V41 | — |
| 6XNC | Salmonella typhimurium tryptophan synthase complexed with L-tryptophan and D-glycerol-3-phosphate | x-ray diffraction | A | 1GP | 7 (best 0.81) |
| 6XNC | Salmonella typhimurium tryptophan synthase complexed with L-tryptophan and D-glycerol-3-phosphate | x-ray diffraction | A | 1GP | — |
| 6XOY | Salmonella typhimurium tryptophan synthase complexed with D-tryptophan and D-glycerol-3-phosphate | x-ray diffraction | A | 1GP | 5 (best 0.82) |
| 6XOY | Salmonella typhimurium tryptophan synthase complexed with D-tryptophan and D-glycerol-3-phosphate | x-ray diffraction | A | 1GP | — |
| 6XRH | Salmonella typhimurium tryptophan synthase complexed with oxindolyl-L-alanine and… | x-ray diffraction | A | 1GP | 6 (best 0.83) |
| 6XRH | Salmonella typhimurium tryptophan synthase complexed with oxindolyl-L- alanine and… | x-ray diffraction | A | 1GP | — |
| 6XT0 | Salmonella typhimurium tryptophan synthase complexed with dioxindolyl-L-alanine and… | x-ray diffraction | A | 1GP | 5 (best 0.81) |
| 6XT0 | Salmonella typhimurium tryptophan synthase complexed with dioxindolyl- L-alanine and… | x-ray diffraction | A | 1GP | — |
| 7A20 | Azobenzene-Based Inhibitors for Tryptophan Synthase | x-ray diffraction | A, B, C, D | NA | 12 (best 0.83) |
| 7A20 | Azobenzene-based inhibitors for tryptophan synthase | x-ray diffraction | A, B, C, D | NA | — |
| 7KWV | The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with… | x-ray diffraction | A | F9F, CL, BCN | 4 (best 0.79) |
| 7KWV | The aminoacrylate form of the wild-type salmonella typhimurium tryptophan synthase in complex with… | x-ray diffraction | A | F9F, CL, BCN | — |
| 7KXC | The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with… | x-ray diffraction | A | F9F, CL | 4 (best 0.82) |
| 7KXC | The aminoacrylate form of the wild-type salmonella typhimurium tryptophan synthase in complex with… | x-ray diffraction | A | F9F, CL | — |
| 7KYT | The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with… | x-ray diffraction | A | F9F, BCN | 5 (best 0.80) |
| 7KYT | The aminoacrylate form of the wild-type salmonella typhimurium tryptophan synthase in complex with… | x-ray diffraction | A | F9F, BCN | — |
| 7L03 | The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with… | x-ray diffraction | A | F9F | 5 (best 0.81) |
| 7L03 | The aminoacrylate form of the wild-type salmonella typhimurium tryptophan synthase in complex with… | x-ray diffraction | A | F9F | — |
| 7LEV | The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with… | x-ray diffraction | A | CL | 4 (best 0.72) |
| 7LEV | The aminoacrylate form of the wild-type salmonella typhimurium tryptophan synthase in complex with… | x-ray diffraction | A | CL | — |
| 7LKL | The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex… | x-ray diffraction | A | F9F, TRP, CS, CL | 8 (best 0.80) |
| 7LKL | The internal aldimine form of the wild-type salmonella typhimurium tryptophan synthase in complex… | x-ray diffraction | A | F9F, CS, CL | — |
| 7MT4 | Crystal structure of tryptophan Synthase in complex with F9, NH4+, pH7.8 - alpha aminoacrylate form… | x-ray diffraction | A | F9F | — |
| 7MT4 | Crystal structure of tryptophan synthase in complex with F9, NH4+, PH7.8 - alpha aminoacrylate form… | x-ray diffraction | A | F9F | — |
| 7MT5 | Crystal structure of tryptophan synthase in complex with F9, Cs+, pH7.8 - alpha aminoacrylate form… | x-ray diffraction | A | F9F | 5 (best 0.81) |
| 7MT5 | Crystal structure of tryptophan synthase in complex with F9, cs+, PH7.8 - alpha aminoacrylate form… | x-ray diffraction | A | F9F | — |
| 7MT6 | Crystal structure of tryptophan synthase in complex with F9, Cs+, benzimidazole, pH7.8 - alpha… | x-ray diffraction | A | F9F | 4 (best 0.80) |
| 7MT6 | Crystal structure of tryptophan synthase in complex with F9, cs+, benzimidazole, PH7.8 - alpha… | x-ray diffraction | A | F9F | — |
Ligands
- F9F · 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate · in 22 records
- CL · Chloride ion · in 18 records
- 1GP · Sn-glycerol-1-phosphate · in 8 records
- BCN · Bicine · in 6 records
- CS · Cesium ion · in 4 records
- NA · Sodium ion · in 2 records
- V41 · (2R,3Z)-3-amino-3-imino-2-[(E)-phenyldiazenyl]propanamide · in 2 records
- SER · Serine · in 1 record
- TRP · Tryptophan · in 1 record
Elsewhere
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