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UniProt A0A0B6A6A8

Isoleucine--tRNA ligase (A0A0B6A6A8)

Isoleucine--tRNA ligase (UniProt A0A0B6A6A8), EC 6.1.1.5: 3 experimental structures on GenesisL1, 7 ligands bound, 23 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A0B6A6A8
Protein
Isoleucine--tRNA ligase
EC
6.1.1.5
Experimental structures
3
Predicted models
0
Ligands
7
Pockets
23 · 2 records with a druggable one

Structures

3 records of A0A0B6A6A8 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8C9EPriestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with an…x-ray diffractionAZN, ILA, SO4, CL, LI, NA12 (best 0.72)
8C9FPriestia megaterium inactive HIGH motif mutant of type1 isoleucyl-tRNA synthetase complexed with an…x-ray diffractionAZN, ILA, SO4, CL, LI, NA11 (best 0.71)
8C9GPriestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with mupirocinx-ray diffractionA, BZN, MRC, CL, NA—

Ligands

  • CL · Chloride ion · in 3 records
  • NA · Sodium ion · in 3 records
  • ZN · Zinc ion · in 3 records
  • ILA · N-[isoleucinyl]-N'-[adenosyl]-diaminosufone · in 2 records
  • LI · Lithium ion · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • MRC · Mupirocin · in 1 record

Elsewhere

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