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Ligand · ILA

ILA · N-[isoleucinyl]-N'-[adenosyl]-diaminosufone

ILA, N-[isoleucinyl]-N'-[adenosyl]-diaminosufone (C16 H26 N8 O6 S, 458.5 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
ILA
Formula
C16 H26 N8 O6 S
Class
ligand
Structures
6
PDB entries
6

Binding sites

ILA in 6 structures; the first of them:

  • 1JZQ · Isoleucyl-tRNA synthetase Complexed with Isoleucyl-adenylate analogue · ILA A1301 · binds GLY45, PRO46, PRO47, HIS54, GLY56, HIS57, GLN59, ASP85 and 10 more
  • 8C8V · Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 with a fully-resolved… · ILA A1103 · binds GLY45, PRO46, PRO47, THR48, HIS54, GLY56, HIS57, ASP85 and 12 more
  • 8C8W · Priestia megaterium mupirocin hyper-resistant HIGH motif mutant of type 2 isoleucyl-tRNA… · ILA A4101 · binds GLY45, PRO46, PRO47, THR48, HIS56, HIS57, ASP85, TRP130 and 12 more
  • 8C9D · Priestia megaterium W130Q mutant of type 2 isoleucyl-tRNA synthetase complexed with an… · ILA A1103 · binds GLY45, PRO46, PRO47, THR48, HIS54, GLY56, HIS57, ASP85 and 11 more
  • 8C9E · Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with an… · ILA A1002 · binds GLY55, PRO56, PRO57, TYR58, HIS64, GLY66, HIS67, ASN70 and 12 more
  • 8C9F · Priestia megaterium inactive HIGH motif mutant of type1 isoleucyl-tRNA synthetase… · ILA A1002 · binds GLY55, PRO56, PRO57, TYR58, HIS66, HIS67, ASN70, ASP95 and 11 more

Residues it binds most

GLY 6, HIS 6, ASP 8, PRO 8, TRP 6, GLN 6, SER 8, LYS 5, GLU 6, THR 5 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • TAR · D(-)-tartaric acid
  • LI · Lithium ion
  • NA · Sodium ion
  • CL · Chloride ion
  • SO4 · Sulfate ion

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