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UniProt A0A0A0MTJ0

Thyrotropin receptor (A0A0A0MTJ0)

Thyrotropin receptor (UniProt A0A0A0MTJ0): 8 experimental structures on GenesisL1, 2 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A0A0MTJ0
Protein
Thyrotropin receptor
Experimental structures
8
Predicted models
0
Ligands
2
Pockets
34 · 4 records with a druggable one

Structures

8 records of A0A0A0MTJ0 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7T9INative human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)electron microscopyRNAG10 (best 0.83)
7T9INative human tsh bound to human thyrotropin receptor in complex with MINIGS399 (composite structure)electron microscopyRNAG—
7T9MHuman Thyrotropin receptor bound by CS-17 Inverse Agonist Fab/Org 274179-0 Antagonistelectron microscopyRNAG7 (best 0.84)
7T9MHuman thyrotropin receptor bound by cs-17 inverse agonist FAB/ORG 274179-0 antagonistelectron microscopyRNAG—
7T9NM22 Agonist Autoantibody bound to Human Thyrotropin receptor in complex with miniGs399 (composite…electron microscopyRZ41, NAG11 (best 0.80)
7T9NM22 agonist autoantibody bound to human thyrotropin receptor in complex with MINIGS399 (composite…electron microscopyRZ41, NAG—
7UTZHuman thyrotropin analog TR1402 bound to human Thyrotropin receptor in complex with miniGs399…electron microscopyRNAG, Z416 (best 0.83)
7UTZHuman thyrotropin analog TR1402 bound to human thyrotropin receptor in complex with MINIGS399…electron microscopyRNAG, Z41—

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
  • Z41 · (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate · in 4 records

Elsewhere

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