UniProt A0A059PIQ0
Green fluorescent protein (A0A059PIQ0)
Green fluorescent protein (UniProt A0A059PIQ0), EC 1.17.4.4: 120 experimental structures on GenesisL1, 27 ligands bound, 194 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A059PIQ0
- Protein
- Green fluorescent protein
- EC
- 1.17.4.4
- Experimental structures
- 120
- Predicted models
- 0
- Ligands
- 27
- Pockets
- 194 · 35 records with a druggable one
Structures
120 records of A0A059PIQ0 in the MolNFT archive: 120 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5BT0 | Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different… | x-ray diffraction | A, B | — | — |
| 5BTT | Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different… | x-ray diffraction | A, B | — | — |
| 5DPG | sfGFP mutant - 133 p-cyano-L-phenylalanine | x-ray diffraction | A | NA | — |
| 5DPG | Sfgfp mutant - 133 P-cyano-L-phenylalanine | x-ray diffraction | A | — | — |
| 5DPH | sfGFP mutant - 149 p-cyano-L-phenylalanine | x-ray diffraction | A, B | CO2, MG | 4 (best 0.81) |
| 5DPH | Sfgfp mutant - 149 P-cyano-L-phenylalanine | x-ray diffraction | A, B | — | — |
| 5DPI | sfGFP double mutant - 133/149 p-cyano-L-phenylalanine | x-ray diffraction | A, B, C, D, E, F | — | 20 (best 0.77) |
| 5DPI | Sfgfp double mutant - 133/149 P-cyano-L-phenylalanine | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5DPJ | sfGFP double mutant - 133/149 p-ethynyl-L-phenylalanine | x-ray diffraction | A, B, C, D | — | — |
| 5DPJ | Sfgfp double mutant - 133/149 P-ethynyl-L-phenylalanine | x-ray diffraction | A, B, C, D | — | — |
| 5DY6 | Enhanced superfolder GFP with DBCO at 148 | x-ray diffraction | A, B | SO4 | — |
| 5DY6 | Enhanced superfolder GFP with dbco at 148 | x-ray diffraction | A, B | — | — |
| 5EHU | sfGFP mutant with unnatural amino acid 4-azidoethoxy-L-phenylalanine incorporated at the 149 site | x-ray diffraction | A, B | — | 3 (best 0.76) |
| 5EHU | Sfgfp mutant with unnatural amino acid 4-azidoethoxy-L-phenylalanine incorporated at the 149 site | x-ray diffraction | A, B | — | — |
| 5JZK | The Structure of Ultra Stable Green Fluorescent Protein | x-ray diffraction | A, B | NO3, CL | 5 (best 0.76) |
| 5JZK | The structure of ultra stable green fluorescent protein | x-ray diffraction | A, B | — | — |
| 5JZL | The Structure of Monomeric Ultra Stable Green Fluorescent Protein | x-ray diffraction | A, B | CL, NA | — |
| 5JZL | The structure of monomeric ultra stable green fluorescent protein | x-ray diffraction | A, B | — | — |
| 5MFC | Designed armadillo repeat protein YIIIM5AII in complex with (KR)4-GFP | x-ray diffraction | B, D | — | — |
| 5MFC | Designed armadillo repeat protein YIIIM5AII in complex with (KR)4-GFP | x-ray diffraction | B, D | CRO | — |
| 5NHN | Super-folder green fluorescent protein artificiall dimer linked via 148 position | x-ray diffraction | B, A | CRO, DB5 | — |
| 5NI3 | sfGFP 204-204 mutant dimer | x-ray diffraction | A, B, C, D | NA, DB5, CL | 12 (best 0.79) |
| 5NI3 | Sfgfp 204-204 mutant dimer | x-ray diffraction | A, B, C, D | CRO, NA, DB5, CL | — |
| 5YR2 | Structure of cpGFP66BPA | x-ray diffraction | A, B | — | 4 (best 0.77) |
| 5YR2 | Structure of CPGFP66BPA | x-ray diffraction | A, B | BF9 | — |
| 5Z6Y | Structure of sfYFP48S95C66BPA | x-ray diffraction | A | — | — |
| 5Z6Y | Structure of SFYFP48S95C66BPA | x-ray diffraction | A | BF6 | — |
| 6B9C | Superfolder green fluorescent protein with 4-nitro-L-phenylalanine at the chromophore (position 66) | x-ray diffraction | A | CO2 | — |
| 6H01 | Crystal structure of a domain-swapped dark-state sfGFP containing the unnatural amino acid… | x-ray diffraction | A, B, C, D | — | — |
| 6H01 | Crystal structure of a domain-swapped dark-state sfgfp containing the unnatural amino acid… | x-ray diffraction | A, B, C, D | FHE | — |
| 6HUT | GFP8 - a stabilized variant of cycle-3 GFP | x-ray diffraction | A | — | — |
| 6HUT | GFP8 - a stabilized variant of cycle-3 GFP | x-ray diffraction | A | CRO | — |
| 6KRG | Crystal structure of sfGFP Y182TMSiPhe | x-ray diffraction | A | CL | — |
| 6KRG | Crystal structure of sfgfp Y182TMSIPHE | x-ray diffraction | A | CRO, CL | — |
| 6OA8 | Superfolder Green Fluorescent Protein with 4-cyano-L-phenylalanine at the chromophore (position 66) | x-ray diffraction | A | SO4, NA | — |
| 6OA8 | Superfolder green fluorescent protein with 4-cyano-L-phenylalanine at the chromophore (position 66) | x-ray diffraction | A | SO4, NA | — |
| 6QUH | Ghk tagged GFP variant crystal form II at 1.34A wavelength | x-ray diffraction | A, C | CRO, CU, CA | — |
| 6UN5 | Crystal structure of green fluorescent protein (GFP); S65T, Y66(2,3,5- F3Y); ih circular permutant… | x-ray diffraction | A, B | QC4 | — |
| 6UN6 | Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-NO2Y); ih circular permutant… | x-ray diffraction | A, B | — | 8 (best 0.77) |
| 6UN6 | Crystal structure of green fluorescent protein (GFP); S65T, Y66(3- NO2Y); ih circular permutant… | x-ray diffraction | A, B | QCA | — |
| 6UN7 | Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-OMeY); ih circular permutant… | x-ray diffraction | A, B | — | 4 (best 0.79) |
| 6UN7 | Crystal structure of green fluorescent protein (GFP); S65T, Y66(3- omey); ih circular permutant… | x-ray diffraction | A, B | QCD | — |
| 6WV3 | Human vkor with warfarin | x-ray diffraction | A | CRO, SWF | — |
| 6WV4 | Human VKOR C43S with warfarin | x-ray diffraction | A | SWF | 2 (best 0.78) |
| 6WV4 | Human vkor C43S with warfarin | x-ray diffraction | A | CRO, SWF | — |
| 6WV5 | Human vkor C43S mutant with vitamin K1 epoxide | x-ray diffraction | A | CRO, UAV | — |
| 6WV6 | Human vkor with phenindione | x-ray diffraction | A | CRO, UAS | — |
| 6WV7 | Human vkor with chlorophacinone | x-ray diffraction | A, B | CRO, UAJ | — |
| 6WV8 | Takifugu rubripes VKOR-like C138S mutant with vitamin K1 | x-ray diffraction | A | PQN | 3 (best 0.78) |
| 6WV8 | Takifugu rubripes vkor-like C138S mutant with vitamin K1 | x-ray diffraction | A | CRO, PQN | — |
| 6WVB | Takifugu rubripes vkor-like with warfarin | x-ray diffraction | A | CRO, SWF | — |
| 6WVH | Human VKOR with Brodifacoum | x-ray diffraction | A, B | UA7 | 6 (best 0.78) |
| 6WVH | Human vkor with brodifacoum | x-ray diffraction | A, B | CRO, UA7 | — |
| 7A7M | rsGreen0.7b in the green-on state | x-ray diffraction | A | — | 1 (best 0.77) |
| 7A7M | RSGREEN0.7B in the green-on state | x-ray diffraction | A | CRO | — |
| 7A7N | rsGreen0.7b in the green-off state | x-ray diffraction | A | — | 1 (best 0.75) |
| 7A7N | RSGREEN0.7B in the green-off state | x-ray diffraction | A | CRO | — |
| 7A7O | rsGreen0.7-K206A in the green-on state | x-ray diffraction | A | — | 1 (best 0.76) |
| 7A7O | RSGREEN0.7-K206A in the green-on state | x-ray diffraction | A | CRO | — |
| 7A7P | RSGREEN0.7-K206A partially in the green-off state | x-ray diffraction | A | CRO, NO3 | — |
60 records more on the page itself.
Ligands
- CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · in 54 records
- CL · Chloride ion · in 7 records
- NA · Sodium ion · in 7 records
- NO3 · Nitrate ion · in 4 records
- SWF · S-warfarin · in 4 records
- DB5 · [(4~{S})-4,5,6,7,8,9-hexahydro-1~{H}-cycloocta[d][1,2, 3]triazol-4-yl] hydrogen carbonate · in 3 records
- SO4 · Sulfate ion · in 3 records
- CLR · Cholesterol · in 2 records
- CO2 · Carbon dioxide · in 2 records
- PQN · Phylloquinone · in 2 records
- UA7 · Brodifacoum · in 2 records
- BF6 · [(4Z)-2-(aminomethyl)-4-{[4-(benzenecarbonyl) phenyl]methylidene}-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · in 1 record
- BF9 · [(4Z)-2-[(1R,2S)-1-amino-2-hydroxypropyl]-4-{[4-(benzenecarbonyl)phenyl]methylidene}-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · in 1 record
- CA · Calcium ion · in 1 record
- CU · Copper (II) ion · in 1 record
- FHE · 2-[(4~{Z})-2-[(1~{R})-1-azanyl-2-oxidanylidene-propyl]-4-[[4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-5-oxidanylidene-imidazol-1-yl]ethanoic acid · in 1 record
- MG · Magnesium ion · in 1 record
- OLA · Oleic acid · in 1 record
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 1 record
- QC4 · {(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-5-oxo-4-[(2, 3,5-trifluoro-4-hydroxyphenyl)methylidene]-4,5-dihydro-1H-imidazol-1-yl}acetic acid · in 1 record
- QCA · {(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-[(4-hydroxy-3-nitrophenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · in 1 record
- QCD · {(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-[(4-hydroxy-3-methoxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl }acetic acid · in 1 record
- UAJ · Chlorophacinone · in 1 record
- UAS · Phenindione · in 1 record
- UAV · (2R,3R)-2-hydroxy-3-methyl-2-[(2E,7S)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-2,3-dihydronaphthalene-1,4-dione · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 6UN7 chain B against the predicted model P42212: TM-score 0.78, RMSD 0.48 Å
- 6UN7 chain B against the predicted model P42212: TM-score 0.78, RMSD 0.48 Å
- 6UN6 chain A against the predicted model P42212: TM-score 0.78, RMSD 0.46 Å
- 6UN6 chain A against the predicted model P42212: TM-score 0.78, RMSD 0.46 Å
- 6UN5 chain A against the predicted model P42212: TM-score 0.77, RMSD 0.36 Å
- 6UN5 chain B against the predicted model P42212: TM-score 0.77, RMSD 0.37 Å
- 6UN7 chain A against the predicted model P42212: TM-score 0.77, RMSD 0.37 Å
- 6UN7 chain A against the predicted model P42212: TM-score 0.77, RMSD 0.37 Å
- 6UN6 chain B against the predicted model P42212: TM-score 0.77, RMSD 0.57 Å
- 6UN6 chain B against the predicted model P42212: TM-score 0.77, RMSD 0.57 Å
Elsewhere
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