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UniProt A0A045H6H0

Isocitrate lyase (A0A045H6H0)

Isocitrate lyase (UniProt A0A045H6H0), EC 4.1.3.1: 4 experimental structures on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A045H6H0
Protein
Isocitrate lyase
EC
4.1.3.1
Experimental structures
4
Predicted models
0
Ligands
4
Pockets
20 · 1 record with a druggable one

Structures

4 records of A0A045H6H0 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6VB9Covalent adduct of cis-2,3-epoxysuccinic acid with Isocitrate Lyase-1 from Mycobacterium…x-ray diffractionA, B, C, DMG, OXD—
6VB9Covalent adduct of cis-2,3-epoxysuccinic acid with isocitrate lyase-1 from mycobacterium…x-ray diffractionA, B, C, DMG, OXD—
6WSIIntact cis-2,3-epoxysuccinic acid bound to Isocitrate Lyase-1 from Mycobacterium tuberculosisx-ray diffractionA, B, C, DMG, GLV, U9S20 (best 0.87)
6WSIIntact cis-2,3-epoxysuccinic acid bound to isocitrate lyase-1 from mycobacterium tuberculosisx-ray diffractionA, B, C, DMG, GLV, U9S—

Ligands

  • MG · Magnesium ion · in 4 records
  • GLV · Glyoxylic acid · in 2 records
  • OXD · Oxalic acid · in 2 records
  • U9S · (2R,3S)-oxirane-2,3-dicarboxylic acid · in 2 records

Elsewhere

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