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Ligand · Z79

Z79 · N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]glycinamide

Z79, N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]glycinamide (C9 H12 N2 O5 S, 260.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
Z79
Formula
C9 H12 N2 O5 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

Z79 in 4 structures; the first of them:

  • 3LK8 · Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor… · Z79 A0 · binds GLY179, ILE180, LEU181, ALA182, HIS183, LEU214, THR215, HIS218 and 8 more
  • 3OHO · catalytic domain of stromelysin-1 in complex with… · Z79 A252 · binds ASN162, VAL163, LEU164, ALA165, HIS166, LEU197, VAL198, HIS201 and 8 more
  • 3LK8 · Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor… · Z79 A0 · binds GLY179, ILE180, LEU181, ALA182, HIS183, LEU214, THR215, HIS218 and 8 more
  • 3OHO · Catalytic domain of stromelysin-1 in complex with N-hydroxy-2-(4… · Z79 A252 · binds ASN162, VAL163, LEU164, ALA165, HIS166, LEU197, VAL198, HIS201 and 8 more

Residues it binds most

HIS 4, LEU 4, TYR 4, VAL 4, ALA 4, GLU 4, PRO 4, THR 2, ASN 2, GLY 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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