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Ligand · XRF

XRF · 1-{2-deoxy-5-O-[(S)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione

XRF, 1-{2-deoxy-5-O-[(S)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione (C10 H17 N2 O14 P3, 482.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
XRF
Formula
C10 H17 N2 O14 P3
Class
ligand
Structures
2
PDB entries
1

Binding sites

XRF in 2 structures; the first of them:

  • 7LSK · Structure of HIV-1 Reverse Transcriptase in complex with DNA, L-dTTP, and CA(2+) ion · XRF A605 · binds LYS65, ARG72, ASP110, VAL111, GLY112, ASP113, ALA114, TYR115 and 7 more
  • 7LSK · Structure of HIV-1 reverse transcriptase in complex with DNA, L-dttp, and CA(2+) ion · XRF A605 · binds LYS65, ARG72, ASP110, VAL111, GLY112, ASP113, ALA114, TYR115 and 7 more

Residues it binds most

ASP 4, LYS 4, ALA 4, ARG 4, DA 4, DC 4, DG 4, GLN 4, GLY 4, MET 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • FRU · beta-D-fructofuranose
  • GLC · alpha-D-glucopyranose
  • NH4 · Ammonium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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