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Ligand · XP2

XP2 · (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate

XP2, (2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl undecanoate (C51 H93 O24 P, 1121.2 g/mol), in…

Component
XP2
Formula
C51 H93 O24 P
Class
ligand
Structures
3
PDB entries
3

Binding sites

XP2 in 3 structures; the first of them:

  • 8E9G · Mycobacterial respiratory complex I with both qui positions modelled · XP2 L701 · binds PRO166, SER167, THR170, LYS173, LYS174, VAL177, VAL178, VAL181 and 16 more
  • 8E9H · Mycobacterial respiratory complex I, fully-inserted qui · XP2 L701 · binds PRO166, SER167, THR170, LYS173, LYS174, VAL177, VAL178, VAL181 and 16 more
  • 8E9I · Mycobacterial respiratory complex I, semi-inserted qui · XP2 L701 · binds PRO166, SER167, THR170, LYS174, VAL177, VAL178, VAL181, LEU226 and 16 more

Residues it binds most

VAL 3, GLN 3, LEU 3, PRO 3, THR 3, LYS 3, MET 3, ASN 3, ASP 3, GLU 3 (residue and the binding sites it lines).

Found with

  • FES · Fe2/s2 (inorganic) cluster
  • FMN · Flavin mononucleotide
  • GTP · Guanosine-5'-triphosphate
  • MQ9 · Menaquinone-9
  • SF4 · Iron/sulfur cluster
  • ZN · Zinc ion

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