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Ligand · UAP

UAP · 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid

UAP, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid (C6 H8 O9 S, 256.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
UAP
Formula
C6 H8 O9 S
Class
sugar
Structures
4
PDB entries
3

Binding sites

UAP in 4 structures; the first of them:

  • 5G2T · BT1596 in complex with its substrate 4,5 unsaturated uronic acid alpha 1,4… · UAP E2 · binds ASP32, HIS33, LEU71, SER72, ASN93, LYS125, HIS127, HIS188 and 7 more
  • 6LJA · Crystal Structure of exoHep from Bacteroides intestinalis DSM 17393 complexed with… · UAP B2 · binds SER226, PHE282, ASN336, HIS337, GLN340, TYR390, HIS555, ARG579 and 2 more
  • 8EDI · Structure of C. elegans UNC-5 IG 1+2 Domains bound to Heparin dp4 · UAP E4 · binds ARG17, MET109, LYS111, ALA187, ASN188, ARG190
  • 6LJA · Crystal structure of exohep from bacteroides intestinalis dsm 17393 complexed with… · UAP B2 · binds SER226, PHE282, ASN336, HIS337, GLN340, TYR390, HIS555, ARG579 and 2 more

Residues it binds most

HIS 6, ARG 7, LYS 5, ASN 7, SER 6, TYR 6, ASP 4, CYS 4, GLU 4, LEU 4 (residue and the binding sites it lines).

Found with

  • SGN · 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose
  • CA · Calcium ion
  • ZN · Zinc ion
  • FUC · alpha-L-fucopyranose
  • IDS · 2-O-sulfo-alpha-L-idopyranuronic acid
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • EDO · 1,2-ethanediol

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