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Ligand · TGG

TGG · Gamma-glutamyl-S-(1,2-dicarboxyethyl)cysteinylglycine

TGG, Gamma-glutamyl-S-(1,2-dicarboxyethyl)cysteinylglycine (C14 H21 N3 O10 S, 423.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
TGG
Formula
C14 H21 N3 O10 S
Class
ligand
Structures
6
PDB entries
3

Binding sites

TGG in 6 structures; the first of them:

  • 2F2K · Aldose reductase tertiary complex with NADPH and DEG · TGG A351 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE121, PHE122 and 6 more
  • 2V6K · Structure of Maleyl Pyruvate Isomerase, a bacterial glutathione-s- transferase in Zeta… · TGG A1213 · binds ARG8, SER9, GLY10, THR11, ARG14, LEU33, HIS38, LEU51 and 13 more
  • 4KAE · Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans… · TGG A301 · binds ARG10, SER11, SER12, SER13, ARG16, LEU35, SER52, GLN53 and 11 more
  • 2F2K · Aldose reductase tertiary complex with NADPH and deg · TGG A351 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE121, PHE122 and 6 more
  • 2V6K · Structure of maleyl pyruvate isomerase, a bacterial glutathione-S- transferase in zeta… · TGG A1213 · binds ARG8, SER9, GLY10, THR11, ARG14, LEU33, HIS38, LEU51 and 13 more
  • 4KAE · Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans… · TGG A301 · binds ARG10, SER11, SER12, SER13, ARG16, LEU35, SER52, GLN53 and 11 more

Residues it binds most

SER 10, ARG 8, GLN 8, ASN 8, LEU 10, PRO 8, HIS 6, VAL 10, TRP 2, ALA 6 (residue and the binding sites it lines).

Found with

  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • NA · Sodium ion
  • ACT · Acetate ion
  • CIT · Citric acid
  • GOL · Glycerol

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