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Ligand · SR6

SR6 · dolastatin-10

SR6, dolastatin-10 (C42 H68 N6 O6 S, 785.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
SR6
Formula
C42 H68 N6 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

SR6 in 2 structures; the first of them:

  • 7TR3 · CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring · SR6 B502 · binds GLN11, GLN15, LYS174, VAL175, SER176, ASP177, TYR208, PRO220 and 3 more
  • 7TR3 · CAKIP3[2-482] - AMP-pnp in complex with a dolastatin-10-stabilized tubulin ring · SR6 B502 · binds GLN11, GLN15, LYS174, VAL175, SER176, ASP177, TYR208, PRO220 and 3 more

Residues it binds most

GLN 2, TYR 2, ASP 2, GLY 2, LYS 2, PRO 2, SER 2, THR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • ANP · Phosphoaminophosphonic acid-adenylate ester
  • GDP · Guanosine-5'-diphosphate
  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion

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