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Ligand · SPL

SPL · Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide

SPL, Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (C26 H51 N O3, 425.7 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
SPL
Formula
C26 H51 N O3
Class
ligand
Structures
3
PDB entries
3

Binding sites

SPL in 3 structures; the first of them:

  • 1MQT · Swine Vesicular Disease Virus coat protein · SPL A284 · binds ILE94, ALA96, ARG97, PHE114, LEU116, LEU118, TYR145, PRO167 and 19 more
  • 8WOQ · Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH · SPL A913 · binds MET548, ALA551, GLU555, MET578, ILE581, CYS585, SER716, LEU719 and 10 more
  • 8WOR · Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH · SPL A912 · binds MET548, ALA551, GLU555, MET578, ILE581, SER716, LEU719, GLY720 and 10 more

Residues it binds most

LEU 5, ILE 5, MET 5, TRP 4, PHE 5, SER 5, ALA 4, CYS 4, GLY 5, GLU 4 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • OLA · Oleic acid
  • CA · Calcium ion
  • ZN · Zinc ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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