GL1X · GenesisL1 explorer

Ligand · Q70

Q70 · Osugacestat

Q70, Osugacestat (C26 H26 F6 N4 O3, 556.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
Q70
Formula
C26 H26 F6 N4 O3
Class
ligand
Structures
1
PDB entries
1

Binding sites

Q70 in 1 structure; the first of them:

  • 8KCS · Cryo-EM structure of human gamma-secretase in complex with BMS906024 · Q70 B502 · binds LEU85, VAL261, LEU268, VAL272, GLN276, LEU282, ARG377, GLY378 and 15 more

Residues it binds most

LEU 1, LYS 1, VAL 1, ALA 1, GLY 1, ARG 1, ASP 1, GLN 1, PRO 1, THR 1 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine
  • BMA · beta-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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