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Ligand · PUL

PUL · (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxoox acyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl 6-deoxy-2,4-di-O-methyl-beta-L-galactopyranoside

PUL, (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxoox acyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl…

Component
PUL
Formula
C47 H66 O13
Class
ligand
Structures
4
PDB entries
2

Binding sites

PUL in 4 structures; the first of them:

  • 2C78 · EF-Tu complexed with a GTP analog and the antibiotic pulvomycin · PUL A1408 · binds ILE89, LYS90, ILE93, THR94, ALA97, GLN98, LEU122, GLN125 and 26 more
  • 4PC7 · Elongation factor Tu:Ts complex in a near GTP conformation. · PUL A402 · binds ASN63, VAL88, LYS89, ILE92, THR93, ALA96, GLN97, LEU121 and 25 more
  • 2C78 · Ef-tu complexed with a GTP analog and the antibiotic pulvomycin · PUL A1408 · binds ILE89, LYS90, ILE93, THR94, ALA97, GLN98, LEU122, GLN125 and 26 more
  • 4PC7 · Elongation factor TU:TS complex in a near GTP conformation. · PUL A402 · binds ASN63, VAL88, LYS89, ILE92, THR93, ALA96, GLN97, LEU121 and 25 more

Residues it binds most

ARG 4, THR 4, PHE 4, VAL 4, ILE 4, ALA 4, GLN 4, GLU 4, GLY 4, ASN 4 (residue and the binding sites it lines).

Found with

  • GNP · Phosphoaminophosphonic acid-guanylate ester
  • MG · Magnesium ion

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