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Ligand · POD

POD · 9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8A,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5ah)-one

POD, 9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8A,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5ah)-one (C22 H22 O8, 414.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
POD
Formula
C22 H22 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

POD in 2 structures; the first of them:

  • 1SA1 · Tubulin-podophyllotoxin: stathmin-like domain complex · POD B700 · binds THR179, VAL181, GLY237, VAL238, THR240, CYS241, LEU242, LEU248 and 17 more
  • 1SA1 · Tubulin-podophyllotoxin: stathmin-like domain complex · POD B700 · binds THR179, VAL181, GLY237, VAL238, THR240, CYS241, LEU242, LEU248 and 17 more

Residues it binds most

VAL 4, ALA 4, THR 4, LEU 4, ASN 4, LYS 4, ASP 4, CYS 4, GLY 4, ILE 4 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion

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