OG6 · 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione

Binding sites

OG6 in 5 structures; the first of them:

• 8I6C · Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with… · OG6 A301 · binds GLY66, GLN67, ASP68, PRO69, TYR70, SER80, PHE81, SER93 and 1 more
• 8K4F · DHODH in complex with compound A0 · OG6 A404 · binds LYS99, ASN144, ARG145, TYR146, GLY147, PHE148, ASN211, SER214 and 4 more
• 9DI6 · Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with… · OG6 A1003 · binds LYS229, ASN274, SER275, CYS276, GLY277, PHE278, ASN342, SER345 and 4 more
• 9DIK · Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with… · OG6 A1003 · binds LYS229, ASN274, SER275, CYS276, GLY277, PHE278, ASN342, SER345 and 4 more
• 9DKQ · Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with… · OG6 A1003 · binds LYS229, ASN274, SER275, CYS276, GLY277, PHE278, ASN342, SER345 and 6 more

Residues it binds most

ASN 6, SER 6, GLY 6, LYS 5, PHE 6, PRO 6, THR 5, CYS 4, TYR 2, ARG 1 (residue and the binding sites it lines).

Found with

• FMN · Flavin mononucleotide
• A1A51 · ethyl 1,4-dimethyl-5-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-1H-pyrazole-3-carboxylate
• A1A52 · N-cyclopropyl-1,4-dimethyl-5-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-1H-pyrazole-3-carboxamide
• A1A5Q · 4,6-dicyclopropyl-3-{[3-fluoro-4-(trifluoromethyl)phenyl]methyl}-2-methyl-2,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one
• FJW · 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
• NA · Sodium ion
• CL · Chloride ion
• SO4 · Sulfate ion
• ACT · Acetate ion
• CIT · Citric acid
• LDA · Lauryl dimethylamine-N-oxide
• PG4 · Tetraethylene glycol