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Ligand · NFV

NFV · Ni-Fe oxidized active center

NFV, Ni-Fe oxidized active center (C3 Fe N2 Ni O2, 210.6 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
NFV
Formula
C3 Fe N2 Ni O2
Class
ligand
Structures
14
PDB entries
10

Binding sites

NFV in 14 structures; the first of them:

  • 5MDK · Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its… · NFV L704 · binds CYS75, VAL77, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530 and 6 more
  • 5XLF · Crystal structure of aerobically purified and aerobically crystallized D. vulgaris… · NFV L601 · binds CYS81, VAL83, CYS84, THR87, HIS88, ALA477, PRO478, ARG479 and 6 more
  • 5XLH · Crystal structure of aerobically purified and aerobically crystallized for 12weeks D.… · NFV L601 · binds CYS81, VAL83, CYS84, THR87, HIS88, ALA477, PRO478, ARG479 and 6 more
  • 5XVD · [NiFe]-hydrogenase (Hyb-type) from Citrobacter sp. S-77 in an air-oxidized condition · NFV L602 · binds CYS61, VAL63, CYS64, THR67, HIS68, ALA477, PRO478, ARG479 and 6 more
  • 8POU · Crystal Structure of the C19G/C120G variant of the membrane-bound [NiFe]-Hydrogenase from… · NFV L701 · binds CYS75, VAL77, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530 and 6 more
  • 5MDJ · Crystal structure of an O2-tolerant [nife]-hydrogenase from ralstonia eutropha in a its… · NFV L701 · binds CYS75, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530, LEU533 and 5 more
  • 5MDK · Crystal structure of an O2-tolerant [nife]-hydrogenase from ralstonia eutropha in its… · NFV L704 · binds CYS75, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530, LEU533 and 5 more
  • 5MDL · Crystal structure of an O2-tolerant [nife]-hydrogenase from ralstonia eutropha in its… · NFV L701 · binds CYS75, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530, LEU533 and 5 more
  • 5XLF · Crystal structure of aerobically purified and aerobically crystallized D. vulgaris… · NFV L601 · binds CYS81, CYS84, THR87, HIS88, ALA477, PRO478, ARG479, LEU482 and 5 more
  • 5XLG · Crystal structure of anaerobically purified and aerobically crystallized D. vulgaris… · NFV L601 · binds CYS81, CYS84, THR87, HIS88, ALA477, PRO478, ARG479, LEU482 and 5 more
  • 5XLH · Crystal structure of aerobically purified and aerobically crystallized for 12WEEKS D.… · NFV L601 · binds CYS81, CYS84, THR87, HIS88, ALA477, PRO478, ARG479, LEU482 and 5 more
  • 5XVC · [nife]-hydrogenase (hyb-type) from citrobacter sp. S-77 in a ferricyanide-oxidized… · NFV L602 · binds CYS61, CYS64, THR67, HIS68, ALA477, PRO478, ARG479, LEU482 and 5 more
  • 5XVD · [nife]-hydrogenase (hyb-type) from citrobacter sp. S-77 in an air- oxidized condition · NFV L602 · binds CYS61, CYS64, THR67, HIS68, ALA477, PRO478, ARG479, LEU482 and 5 more
  • 7ODH · Crystal structure of the O2-tolerant mbh-P242C from ralstonia eutropha in its as-isolated… · NFV L701 · binds CYS75, CYS78, CYS81, HIS82, ALA528, PRO529, ARG530, LEU533 and 5 more

Residues it binds most

CYS 17, PRO 17, VAL 17, ALA 17, ARG 17, HIS 17, LEU 17, THR 17, CSO 11, SER 11 (residue and the binding sites it lines).

Found with

  • SF4 · Iron/sulfur cluster
  • MG · Magnesium ion
  • F3S · FE3-S4 cluster
  • CL · Chloride ion
  • F4S · FE4-S3 cluster
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • 8JU · FE4-S4-O cluster
  • NA · Sodium ion
  • O · Oxygen atom
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether
  • OXY · Oxygen molecule

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