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Ligand · LPR

LPR · [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline

LPR, [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline (C21 H31 N3 O5, 405.5 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
LPR
Formula
C21 H31 N3 O5
Class
ligand
Structures
7
PDB entries
4

Binding sites

LPR in 7 structures; the first of them:

  • 1J36 · Crystal Structure of Drosophila AnCE · LPR A801 · binds ARG51, GLU150, GLN265, HIS337, ALA338, SER339, THR364, HIS367 and 10 more
  • 1O86 · Crystal Structure of Human Angiotensin Converting Enzyme in complex with lisinopril. · LPR A702 · binds GLU162, GLN281, HIS353, ALA354, SER355, ASP377, VAL380, HIS383 and 10 more
  • 2X91 · Crystal structure of AnCE-lisinopril complex · LPR A1615 · binds GLN265, HIS337, ALA338, SER339, THR364, HIS367, GLU368, HIS371 and 9 more
  • 1J36 · Crystal structure of drosophila ance · LPR A801 · binds ARG51, GLU150, GLN265, HIS337, ALA338, SER339, THR364, HIS367 and 10 more
  • 1O86 · Crystal structure of human angiotensin converting enzyme in complex with lisinopril. · LPR A702 · binds GLU162, GLN281, HIS353, ALA354, SER355, ASP377, VAL380, HIS383 and 10 more
  • 2C6N · Structure of human somatic angiontensin-I converting enzyme N domain with lisinopril · LPR A705 · binds GLN259, HIS331, ALA332, SER333, GLN355, THR358, HIS361, GLU362 and 9 more
  • 2X91 · Crystal structure of ance-lisinopril complex · LPR A1615 · binds GLN265, HIS337, ALA338, SER339, THR364, HIS367, GLU368, HIS371 and 9 more

Residues it binds most

HIS 10, GLU 10, TYR 10, PHE 10, GLN 10, ALA 10, LYS 10, SER 10, THR 8, VAL 8 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • GLY · Glycine
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • ACT · Acetate ion
  • GOL · Glycerol

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