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Ligand · KNW

KNW · (2~{S})-8-[[4-[4-(2-chloranyl-5-fluoranyl-phenyl) butoxy]phenyl]carbonylamino]-4-(4-oxidanyl-4-oxidanylidene-butyl)-2,3- dihydro-1,4-benzoxazine-2-carboxylic acid

KNW, (2~{S})-8-[[4-[4-(2-chloranyl-5-fluoranyl-phenyl) butoxy]phenyl]carbonylamino]-4-(4-oxidanyl-4-oxidanylidene-butyl)-2,3- dihydro-1,4-benzoxazine-2-carboxylic acid (C30 H30 Cl F N2 O7, 585.0 g/mol), in the MolNFT structures on…

Component
KNW
Formula
C30 H30 Cl F N2 O7
Class
ligand
Structures
3
PDB entries
2

Binding sites

KNW in 3 structures; the first of them:

  • 6RZ7 · Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with… · KNW A2001 · binds LYS37, PHE41, TYR98, SER115, TYR119, TYR123, TYR127, ILE166 and 22 more
  • 6RZ6 · Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with… · KNW A2001 · binds LYS37, PHE41, TYR119, TYR123, TYR127, SER169, SER170, LEU188 and 14 more
  • 6RZ7 · Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with… · KNW A2001 · binds LYS37, SER115, TYR119, TYR123, TYR127, SER169, SER170, LEU173 and 15 more

Residues it binds most

LEU 3, TYR 3, SER 3, HIS 3, LYS 3, ILE 3, ALA 3, ARG 3, ASN 3, GLY 3 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • OLA · Oleic acid
  • OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
  • PGE · Triethylene glycol
  • 1PE · Pentaethylene glycol
  • TLA · L(+)-tartaric acid

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