KFV · [1-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-1-oxidanylidene-propan-2-ylidene]-bis(oxidanidyl)azanium

Binding sites

KFV in 11 structures; the first of them:

• 6N92 · Methylmalonyl-CoA decarboxylase in complex with 2-nitronate-propionyl-CoA · KFV A301 · binds LEU25, LYS60, ALA64, GLY65, HIS66, ASP67, ILE68, HIS69 and 12 more
• 6X7L · LnmK in complex with 2-nitronate-propionyl-CoA · KFV A402 · binds TRP39, LEU63, ALA64, PHE65, TYR66, ARG140, VAL142, LEU153 and 11 more
• 6XBS · Streptomyces coelicolor methylmalonyl-CoA epimerase (E43Q) in complex with… · KFV A204 · binds HIS7, ASN36, GLN39, VAL41, GLN43, GLN60, ALA70, VAL71 and 17 more
• 6XBV · Streptomyces coelicolor methylmalonyl-CoA epimerase (S115T) in complex with… · KFV A205 · binds HIS7, ASN36, GLN39, GLU43, GLN60, ALA70, VAL71, LYS73 and 13 more
• 6N92 · Methylmalonyl-CoA decarboxylase in complex with 2-nitronate-propionyl- CoA · KFV A301 · binds LEU25, LYS60, ALA64, GLY65, HIS66, ASP67, ILE68, HIS69 and 12 more
• 6WFI · Methylmalonyl-CoA epimerase in complex with 2-nitronate-propionyl-CoA · KFV A206 · binds HIS7, ASN36, GLN39, GLU43, GLN60, ALA70, VAL71, LYS73 and 14 more
• 6X7L · Lnmk in complex with 2-nitronate-propionyl-CoA · KFV A402 · binds TRP39, ALA64, PHE65, TYR66, ARG140, LEU153, LYS155, ASN216 and 8 more
• 6XBR · Streptomyces coelicolor methylmalonyl-CoA epimerase (E43L) in complex with… · KFV A206 · binds HIS7, ASN36, GLN39, LEU43, GLN60, ALA70, VAL71, LYS73 and 13 more
• 6XBS · Streptomyces coelicolor methylmalonyl-CoA epimerase (E43Q) in complex with… · KFV A204 · binds HIS7, ASN36, GLN39, GLN43, GLN60, ALA70, VAL71, LYS73 and 15 more
• 6XBT · Streptomyces coelicolor methylmalonyl-CoA epimerase (Q60A) in complex with… · KFV A204 · binds HIS7, GLN39, VAL41, GLU43, ALA70, VAL71, LYS73, TRP74 and 14 more
• 6XBV · Streptomyces coelicolor methylmalonyl-CoA epimerase (S115T) in complex with… · KFV A205 · binds HIS7, ASN36, GLN39, GLU43, GLN60, ALA70, VAL71, LYS73 and 13 more

Residues it binds most

LEU 21, HIS 25, GLY 17, LYS 21, VAL 26, PHE 27, TRP 27, PRO 23, TYR 19, ALA 23 (residue and the binding sites it lines).

Found with

• SO4 · Sulfate ion
• CO · Cobalt (II) ion
• CL · Chloride ion
• KG7 · (2E)-2-(hydroxyimino)propanoic acid
• K · Potassium ion
• NI · Nickel (II) ion
• IMD · Imidazole
• PG4 · Tetraethylene glycol
• COA · Coenzyme A
• NH4 · Ammonium ion
• PEG · Di(hydroxyethyl)ether