Ligand · ISZ
ISZ · 4-(diazenylcarbonyl)pyridine
ISZ, 4-(diazenylcarbonyl)pyridine (C6 H5 N3 O, 135.1 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…
- Component
- ISZ
- Formula
- C6 H5 N3 O
- Class
- ligand
- Structures
- 16
- PDB entries
- 8
Binding sites
ISZ in 16 structures; the first of them:
- 1W6F · Arylamine N-acetyltransferase from Mycobacterium smegmatis with the anti-tubercular drug… · ISZ A1276 · binds PHE38, TYR69, CYS70, TYR71, VAL95, THR109, HIS110, GLY129 and 3 more
- 1XR3 · Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound · ISZ A263 · binds SER144, THR145, GLY146, GLN149, VAL151, TYR157, GLY188, PHE189 and 1 more
- 2V2E · Structure of isoniazid (INH) bound to cytochrome c peroxidase mutant N184R Y36A · ISZ A1296 · binds ARG48, TRP51, HIS52, SER81, LEU144, PRO145, ASP146, ALA147 and 1 more
- 2VCF · Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase · ISZ X1252 · binds ARG38, HIS42, SER69, ALA70, ASN72, PRO132, ASP133, ALA134 and 2 more
- 2VCN · Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant W41A · ISZ A1254 · binds ARG38, ALA41, HIS42, GLY45, LEU131, PRO132, PHE145, MET149 and 1 more
- 2VCS · Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant H42A · ISZ A1252 · binds ARG38, TRP41, SER69, ALA70, PRO132, SER173
- 3I6N · Mode of Binding of the Tuberculosis Prodrug Isoniazid to Peroxidases: Crystal Structure… · ISZ A607 · binds GLN105, HIS109, ARG255, GLU258, PHE381, PHE422, GLN423, PRO424
- 3U72 · Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Isoniazid at 2.2 A… · ISZ A4611 · binds THR430, GLU431, GLY432, VAL591, ALA592, PRO593, ASN594, TYR660
- 1W6F · Arylamine N-acetyltransferase from mycobacterium smegmatis with the anti-tubercular drug… · ISZ A1276 · binds PHE38, TYR69, CYS70, TYR71, VAL95, THR109, HIS110, GLY129 and 3 more
- 1XR3 · Actinorhodin polyketide ketoreductase with NADP and the inhibitor isoniazid bound · ISZ A263 · binds SER144, THR145, GLY146, GLN149, VAL151, TYR157, GLY188, PHE189 and 1 more
- 2V2E · Structure of isoniazid (inh) bound to cytochrome C peroxidase mutant N184R Y36A · ISZ A1296 · binds ARG48, TRP51, HIS52, SER81, LEU144, PRO145, ASP146, ALA147 and 1 more
- 2VCF · Structure of isoniazid (inh) bound to cytosolic soybean ascorbate peroxidase · ISZ X1252 · binds ARG38, HIS42, SER69, ALA70, ASN72, PRO132, ASP133, ALA134 and 2 more
- 2VCN · Structure of isoniazid (inh) bound to cytosolic soybean ascorbate peroxidase mutant W41A · ISZ A1254 · binds ARG38, ALA41, HIS42, GLY45, LEU131, PRO132, PHE145, MET149 and 1 more
- 2VCS · Structure of isoniazid (inh) bound to cytosolic soybean ascorbate peroxidase mutant H42A · ISZ A1252 · binds ARG38, TRP41, SER69, ALA70, PRO132, SER173
- 3I6N · Mode of binding of the tuberculosis prodrug isoniazid to peroxidases: crystal structure… · ISZ A607 · binds GLN105, HIS109, ARG255, GLU258, PHE381, PHE422, GLN423, PRO424
- 3U72 · Crystal structure of C-lobe of bovine lactoferrin complexed with isoniazid at 2.2 a… · ISZ A4611 · binds THR430, GLU431, GLY432, VAL591, ALA592, PRO593, ASN594, TYR660
Residues it binds most
PHE 16, ARG 18, VAL 14, TYR 14, GLY 16, HIS 18, LEU 14, SER 12, ALA 12, PRO 16 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.