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Ligand · HNO

HNO · N-tert-butyl-6,7-bis(chloranyl)quinoxalin-2-amine

HNO, N-tert-butyl-6,7-bis(chloranyl)quinoxalin-2-amine (C12 H13 Cl2 N3, 270.2 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
HNO
Formula
C12 H13 Cl2 N3
Class
ligand
Structures
7
PDB entries
4

Binding sites

HNO in 7 structures; the first of them:

  • 7DUR · Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex · HNO R701 · binds CYS347
  • 7E14 · Compound2_GLP-1R_OWL833_Gs complex structure · HNO R507 · binds CYS347
  • 7EVM · Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex · HNO R501 · binds CYS347
  • 7DUQ · Cryo-EM structure of the compound 2 and glp-1-bound human glp-1 receptor-gs complex · HNO R501 · binds CYS347
  • 7DUR · Cryo-EM structure of the compound 2-bound human glp-1 receptor-gs complex · HNO R701 · binds CYS347
  • 7E14 · COMPOUND2_GLP-1R_OWL833_GS complex structure · HNO R507 · binds CYS347
  • 7EVM · Cryo-EM structure of the compound 2-bound human glp-1 receptor-gs complex · HNO R501 · binds CYS347

Residues it binds most

CYS 7 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • V6G · 3-[(1S,2S)-1-(5-[(4S)-2,2-dimethyloxan-4-yl]-2-{(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carbonyl}-1H-indol-1-yl)-2-methylcyclopropyl]-1,2,4-oxadiazol-5(4H)-one

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