GL1X · GenesisL1 explorer

Ligand · HAE

HAE · Acetohydroxamic acid

HAE, Acetohydroxamic acid (C2 H5 N O2, 75.1 g/mol), in the MolNFT structures on GenesisL1: bound in 13 records (9 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
HAE
Formula
C2 H5 N O2
Class
ligand
Structures
13
PDB entries
9

Binding sites

HAE in 13 structures; the first of them:

  • 5N5K · Human catalytic MMP-12 in complex with 5-(1,2-dithiolan-3-yl)-N-(3-hydroxypropyl)pentanami… · HAE A306 · binds ILE180, ALA182, HIS183, HIS218, GLU219, HIS222, HIS228
  • 6OT4 · Bimetallic dodecameric cage design 2 (BMC2) from cytochrome cb562 · HAE A202 · binds CYS63, TRP66, TRP66
  • 6OT9 · Bimetallic dodecameric cage design 1 (BMC1) from cytochrome cb562 · HAE C203 · binds CYS63, GLU67, SER59, TRP66
  • 6OVH · Cryo-EM structure of Bimetallic dodecameric cage design 3 (BMC3) from cytochrome cb562 · HAE A202 · binds CYS63, CYS63
  • 5N5J · Human MMP12 in complex with 3-(5-(1,2-dithiolan-3-YL)PENTANAMIDO) propane-1-sulfonate · HAE A306 · binds ALA182, HIS183, HIS218, GLU219, HIS222, HIS228
  • 5N5K · Human catalytic mmp-12 in complex with 5-(1,2-dithiolan-3-yl)-N-(3… · HAE A306 · binds ILE180, ALA182, HIS183, HIS218, GLU219, HIS222, HIS228
  • 6OT4 · Bimetallic dodecameric cage design 2 (BMC2) from cytochrome CB562 · HAE A202 · binds CYS63, TRP66, TRP66

Residues it binds most

CYS 81, ALA 41, HIS 5, LYS 11, TRP 13, GLU 8, SER 6, GLN 4, ILE 4, THR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • HEC · Heme C
  • FE · Fe (III) ion
  • CA · Calcium ion
  • 8NW · 5-[(3~{S})-1,2-dithiolan-3-yl]-~{N}-(3-oxidanylpropyl) pentanamide
  • 8NT · 3-[5-[(3~{S})-1,2-dithiolan-3-yl]pentanoylamino]propane-1-sulfonic acid
  • 1PE · Pentaethylene glycol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.