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Ligand · GVU

GVU · (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl) oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid

GVU, (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)…

Component
GVU
Formula
C36 H52 O11
Class
ligand
Structures
2
PDB entries
1

Binding sites

GVU in 2 structures; the first of them:

  • 7D5C · IleRS in complex with a tRNA site inhibitor · GVU A1001 · binds PHE48, HIS54, GLY88, VAL89, PRO90, PHE191, TRP402, TRP449 and 18 more
  • 7D5C · Ilers in complex with a tRNA site inhibitor · GVU A1001 · binds PHE48, GLY88, VAL89, PRO90, PHE191, TRP402, ARG454, TRP456 and 13 more

Residues it binds most

ARG 2, TRP 2, ASP 2, GLY 2, PHE 2, SER 2, CYS 2, GLN 2, LYS 2, PRO 2 (residue and the binding sites it lines).

Found with

  • GV6 · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (2S,3S)-2-azanyl-3-methyl-pentanoate
  • EDO · 1,2-ethanediol

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