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Ligand · G6S

G6S · 6-O-sulfo-beta-D-galactopyranose

G6S, 6-O-sulfo-beta-D-galactopyranose (C6 H12 O9 S, 260.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
G6S
Formula
C6 H12 O9 S
Class
sugar
Structures
6
PDB entries
4

Binding sites

G6S in 6 structures; the first of them:

  • 2N7B · Solution structure of the human Siglec-8 lectin domain in complex with 6'sulfo sialyl… · G6S B2 · binds ARG56, TYR58, GLN59
  • 3P5I · Structure of the carbohydrate-recognition domain of human Langerin with 6-SO4-Gal-GlcNAc · G6S E2 · binds ILE250, GLU285, ASN287, ALA289, GLU293, ASN297, LYS299, ASN307 and 5 more
  • 7OZC · Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota… · G6S AAA601 · binds ASP42, ASP43, THR81, SER82, ILE103, LYS135, HIS137, THR169 and 13 more
  • 7OZE · Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota… · G6S AAA601 · binds ASP39, ASP40, THR78, SER79, ILE100, LYS132, HIS134, THR168 and 12 more
  • 2N7B · Solution structure of the human siglec-8 lectin domain in complex with 6'SULFO sialyl… · G6S B2 · binds ARG56, TYR58, GLN59
  • 3P5I · Structure of the carbohydrate-recognition domain of human langerin with 6-SO4-gal-glcnac · G6S E2 · binds ILE250, GLU285, ASN287, ALA289, GLU293, ASN297, LYS299, ASN307 and 5 more

Residues it binds most

ASP 13, ASN 13, LYS 13, HIS 5, ILE 13, ALA 8, GLU 8, THR 5, PHE 8, ARG 7 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • 0D8 · 3-aminopropan-1-ol
  • FUC · alpha-L-fucopyranose
  • SIA · N-acetyl-alpha-neuraminic acid

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