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Ligand · G1G

G1G · 7-methyl-guanosine-5'-triphosphate-5'-(2'-O-methyl)-guanosine

G1G, 7-methyl-guanosine-5'-triphosphate-5'-(2'-O-methyl)-guanosine (C22 H32 N10 O18 P3 +1, 817.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
G1G
Formula
C22 H32 N10 O18 P3 +1
Class
ligand
Structures
2
PDB entries
1

Binding sites

G1G in 2 structures; the first of them:

  • 2P41 · Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppG2'OMe and… · G1G A1001 · binds LYS14, LEU17, ASN18, ALA19, LEU20, LYS22, PHE25, LYS29 and 5 more
  • 2P41 · Crystal structure of dengue methyltransferase in complex with 7MEGPPPG2'OME and… · G1G A1001 · binds LYS14, LEU17, ASN18, ALA19, LEU20, LYS22, PHE25, LYS29 and 5 more

Residues it binds most

LYS 2, SER 2, LEU 2, ALA 2, ASN 2, GLU 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • SAH · S-adenosyl-L-homocysteine
  • SO4 · Sulfate ion
  • CIT · Citric acid
  • GOL · Glycerol

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