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Ligand · FZZ

FZZ · 1-deoxy-5-O-phosphono-1-[(10AR)-2,2,3,4-tetramethyl-8, 10-dioxo-1,2,8,9,10,10A-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol

FZZ, 1-deoxy-5-O-phosphono-1-[(10AR)-2,2,3,4-tetramethyl-8, 10-dioxo-1,2,8,9,10,10A-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol (C22 H29 N4 O9 P, 524.5 g/mol), in the MolNFT structures on GenesisL1: bound in 5…

Component
FZZ
Formula
C22 H29 N4 O9 P
Class
ligand
Structures
5
PDB entries
4

Binding sites

FZZ in 5 structures; the first of them:

  • 4ZA7 · Structure of A. niger Fdc1 in complex with alpha-methyl cinnamic acid · FZZ A602 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 18 more
  • 4ZAB · Structure of A. niger Fdc1 in complex with alpha-fluoro cinnamic acid · FZZ A602 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 18 more
  • 6EV6 · Structure of E282Q A. niger Fdc1 with prFMN in the hydroxylated and ketimine forms · FZZ A604 · binds GLN152, THR153, ASN168, TRP169, SER170, ILE171, ALA172, ARG173 and 22 more
  • 6EV3 · Structure of wild type a. niger FDC1 that has been illuminated with UV light, with prfmn… · FZZ A605 · binds THR153, ASN168, TRP169, SER170, ILE171, ALA172, GLN190, HIS191 and 12 more
  • 6EV6 · Structure of E282Q a. niger FDC1 with prfmn in the hydroxylated and ketimine forms · FZZ A604 · binds THR153, ASN168, TRP169, SER170, ILE171, ALA172, ARG173, GLN190 and 13 more

Residues it binds most

SER 5, ILE 5, THR 5, GLU 5, MET 5, GLN 5, ALA 5, ASN 5, HIS 5, LEU 5 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • MN · Manganese (II) ion
  • 4LU · 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-yl)-D-ribitol
  • BYN · hydroxylated prenyl-FMN
  • 4LV · (2E)-2-methyl-3-phenylprop-2-enoic acid
  • 4LW · (2Z)-2-fluoro-3-phenylprop-2-enoic acid

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