4LU · 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-yl)-D-ribitol

Binding sites

4LU in 37 structures; the first of them:

• 4ZA7 · Structure of A. niger Fdc1 in complex with alpha-methyl cinnamic acid · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 20 more
• 4ZAB · Structure of A. niger Fdc1 in complex with alpha-fluoro cinnamic acid · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 19 more
• 5M1D · Crystal structure of N-terminally tagged UbiD from E. coli reconstituted with prFMN… · 4LU A502 · binds THR160, TRP161, ASN175, LEU176, GLY177, ILE178, TYR179, ARG180 and 13 more
• 5O3N · Crystal structure of E. cloacae 3,4-dihydroxybenzoic acid decarboxylase (AroY)… · 4LU A508 · binds CYS150, ASP166, VAL167, THR168, ILE169, HIS170, ARG171, PHE183 and 15 more
• 6EV4 · Structure of wild type A. niger Fdc1 purified in the dark with prFMN in the iminium form · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 20 more
• 6EV7 · Structure of E282D A. niger Fdc1 with prFMN in the iminium form · 4LU A604 · binds THR153, ASN168, TRP169, SER170, ILE171, ALA172, ARG173, GLN190 and 12 more
• 6EVB · Structure of E282Q A. niger Fdc1 with prFMN in the iminium form · 4LU A601 · binds THR153, ASN168, TRP169, SER170, ILE171, ALA172, ARG173, LEU185 and 12 more
• 6EVE · Structure of R175A S. cerevisiae Fdc1 with prFMN in the iminium form · 4LU A601 · binds THR155, TYR156, ASN170, TRP171, SER172, ILE173, ALA174, ALA175 and 15 more
• 6EVF · Structure of E285D S. cerevisiae Fdc1 with prFMN in the hydroxylated form · 4LU A601 · binds THR155, ASN170, SER172, ILE173, ALA174, ARG175, LEU187, GLN192 and 12 more
• 6H6X · Structure of an evolved dimeric form of the UbiD-class enzyme HmfF from Pelotomaculum… · 4LU B503 · binds THR132, ASN147, VAL148, SER149, ILE150, HIS151, ARG152, LEU164 and 11 more
• 6R2T · Aspergillus niger ferulic acid decarboxylase (Fdc) in complex with prFMN (purified in the… · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 19 more
• 6R3O · Aspergillus niger ferric acid decarboxylase (Fdc) L439G variant in complex with prFMN… · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 20 more
• 7NEY · Structure of T. atroviride Fdc wild-type (TaFdc) in complex with prFMN · 4LU A601 · binds GLN162, THR163, TYR164, ASN178, TRP179, SER180, ILE181, ALA182 and 20 more
• 7NF3 · Structure of A. niger Fdc T395M variant (AnFdcI) in complex with prFMN · 4LU A603 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 21 more
• 7P9Q · Crystal structure of Indole 3-Carboxylic acid decarboxylase from Arthrobacter nicotianae… · 4LU A503 · binds ASP135, ASN150, THR151, SER152, ILE153, GLN154, ARG155, ASN167 and 17 more
• 7PDA · Crystal structure of Phenazine 1-carboxylic acid decarboxylase from Mycobacterium… · 4LU A502 · binds GLY144, THR145, ASN160, VAL161, GLY162, THR163, TYR164, ARG165 and 16 more
• 8OEH · Aspergillus niger ferulic acid decarboxylase (Fdc) C122-S261C (DB3) variant in complex… · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 20 more
• 8OEO · Aspergillus niger ferulic acid decarboxylase (Fdc) V186C-A296C (DB4) variant in complex… · 4LU A601 · binds GLN152, THR153, TYR154, ASN168, TRP169, SER170, ILE171, ALA172 and 20 more
• 5M1D · Crystal structure of N-terminally tagged ubid from E. COLI reconstituted with prfmn… · 4LU A502 · binds THR160, TRP161, ASN175, LEU176, ILE178, TYR179, ARG180, ARG192 and 9 more
• 5O3N · Crystal structure of E. cloacae 3,4-dihydroxybenzoic acid decarboxylase (aroy)… · 4LU A508 · binds CYS150, ASP166, THR168, ILE169, HIS170, ARG171, PHE183, LEU184 and 11 more
• 6EV3 · Structure of wild type a. niger FDC1 that has been illuminated with UV light, with prfmn… · 4LU A601 · binds THR153, ASN168, TRP169, SER170, ILE171, ALA172, ARG173, GLN190 and 12 more

Residues it binds most

SER 60, ILE 70, THR 72, GLU 72, ALA 72, ARG 64, HIS 64, PRO 62, ASN 66, LEU 54 (residue and the binding sites it lines).

Found with

• MN · Manganese (II) ion
• K · Potassium ion
• NA · Sodium ion
• JQ8 · phenylpropiolic acid
• SCN · Thiocyanate ion
• FZZ · 1-deoxy-5-O-phosphono-1-[(10AR)-2,2,3,4-tetramethyl-8, 10-dioxo-1,2,8,9,10,10A-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol
• CA · Calcium ion
• PO4 · Phosphate ion
• SO4 · Sulfate ion
• GOL · Glycerol
• 4LV · (2E)-2-methyl-3-phenylprop-2-enoic acid
• 4LW · (2Z)-2-fluoro-3-phenylprop-2-enoic acid