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Ligand · FVZ

FVZ · (2~{S})-2-[[(2~{S})-6-[(4-fluorophenyl)amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid

FVZ, (2~{S})-2-[[(2~{S})-6-[(4-fluorophenyl)amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid (C18 H22 F N3 O8, 427.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
FVZ
Formula
C18 H22 F N3 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

FVZ in 2 structures; the first of them:

  • 6H7Y · X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a… · FVZ A833 · binds LYS207, VAL208, PHE209, ARG210, ASN257, ASP387, GLU424, GLU425 and 16 more
  • 6H7Y · X-ray structure of human glutamate carboxypeptidase II (gcpii) in complex with a… · FVZ A833 · binds LYS207, VAL208, PHE209, ARG210, ASN257, ASP387, GLU424, GLU425 and 16 more

Residues it binds most

ARG 2, GLY 2, ASN 2, ASP 2, GLU 2, LYS 2, PHE 2, SER 2, TYR 2, HIS 2 (residue and the binding sites it lines).

Found with

  • TAM · Tris(hydroxyethyl)aminomethane
  • CA · Calcium ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • PGE · Triethylene glycol

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