Ligand · F86
F86 · [(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-F][1, 2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
F86, [(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-F][1, 2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate (C12 H14 N5 O7 P, 371.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5…
- Component
- F86
- Formula
- C12 H14 N5 O7 P
- Class
- ligand
- Structures
- 5
- PDB entries
- 5
Binding sites
F86 in 5 structures; the first of them:
- 7B3B · Structure of elongating SARS-cov-2 RNA-dependent RNA polymerase with remdesivir at… · F86 P13 · binds GLN815, ARG836, ALA840, ASP865, G12, U14, A10, U11 and 1 more
- 7B3C · Structure of elongating SARS-cov-2 RNA-dependent RNA polymerase with remdesivir at… · F86 P12 · binds ARG836, ALA840, ASP865, C11, G13, U12, G13
- 7BV2 · The NSP12-NSP7-NSP8 complex bound to the template-primer RNA and triphosphate form of… · F86 P101 · binds LYS545, ARG555, ASP623, SER682, THR687, ASN691, ASP760, U20 and 2 more
- 7C2K · COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex · F86 G4 · binds LEU758, SER759, SER814, U-4, C-3, G3, G5
- 7L1F · SARS-cov-2 rdrp in complex with 4 remdesivir monophosphate · F86 P14 · binds ARG836, U13, U4, A5
Residues it binds most
U 8, ASP 5, ARG 6, SER 5, G 3, A 3, ALA 3, C 3, ASN 2, CYS 2 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.