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Ligand · EKI

EKI · 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide

EKI, 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide (C13 H15 N5 O3, 289.3 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues…

Component
EKI
Formula
C13 H15 N5 O3
Class
ligand
Structures
1
PDB entries
1

Binding sites

EKI in 1 structure; the first of them:

  • 8GM4 · Functional construct of the Eukaryotic elongation factor 2 kinase bound to an… · EKI A802 · binds GLY139, ARG140, ARG144, CYS146, VAL168, LYS170, GLU229, HIS230 and 5 more

Residues it binds most

ARG 1, TYR 1, ASP 1, CYS 1, GLU 1, GLY 1, HIS 1, ILE 1, LYS 1, THR 1 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • CA · Calcium ion
  • ZN · Zinc ion

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