Ligand · EAM
EAM · 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
EAM, 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide (C22 H22 Cl N5 O2, 423.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding…
- Component
- EAM
- Formula
- C22 H22 Cl N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 2
Binding sites
EAM in 2 structures; the first of them:
- 5DFC · Crystal structure of BRD2(BD2) W370F mutant with ligand I-BET 762 bound · EAM A503 · binds PHE370, PRO371, PHE372, VAL376, LEU383, ASN429, ASP434, VAL435 and 1 more
- 7AQT · NMR2 structure of BRD4-BD2 in complex with ibet-762 · EAM A201 · binds TRP27, PRO28, VAL33, LEU38, LEU40, CYS82, TYR85, ASN86 and 2 more
Residues it binds most
VAL 2, LEU 2, ASN 2, PHE 1, PRO 2, ASP 1, CYS 1, HIS 1, MET 1, TRP 1 (residue and the binding sites it lines).
Found with
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