E4M · 1-{4-[(6s,6ar,7r)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6, 6A,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol

Binding sites

E4M in 5 structures; the first of them:

• 6HAV · Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with… · E4M A412 · binds SER13, HIS14, CYS17, LYS113, PRO114, PRO150, LYS151, CYS176 and 5 more
• 6HUX · HmdII from Methanocaldococcus jannaschii reconstitued with Fe-guanylylpyridinol (FeGP)… · E4M A412 · binds LEU24, TYR25, LEU29, PHE102, CYS127, ALA157, VAL159, ALA212 and 3 more
• 6HAE · Crystal structure of [fe]-hydrogenase (hmd) from methanococcus aeolicus in complex with… · E4M A402 · binds SER13, HIS14, CYS17, LYS113, PRO114, PRO150, LYS151, CYS176 and 10 more
• 6HAV · Crystal structure of [fe]-hydrogenase (hmd) from methanococcus aeolicus in complex with… · E4M A412 · binds SER13, HIS14, CYS17, LYS113, PRO114, PRO150, LYS151, CYS176 and 5 more
• 6HUX · Hmdii from methanocaldococcus jannaschii reconstitued with fe- guanylylpyridinol (fegp)… · E4M A412 · binds LEU24, TYR25, LEU29, PHE102, CYS127, ALA157, VAL159, ALA212 and 3 more

Residues it binds most

CYS 6, SER 6, PRO 4, LYS 4, MET 6, ASP 6, ALA 2, GLY 4, HIS 4, LEU 2 (residue and the binding sites it lines).

Found with

• FE9 · iron-guanylyl pyridinol cofactor
• NA · Sodium ion
• CL · Chloride ion
• SCN · Thiocyanate ion
• GOL · Glycerol
• MG · Magnesium ion
• SO4 · Sulfate ion
• ACT · Acetate ion
• EDO · 1,2-ethanediol
• K · Potassium ion
• 2PE · Nonaethylene glycol