GL1X · GenesisL1 explorer

Ligand · E40

E40 · (2R)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-2-{[(4'-methoxybiphenyl-4-yl)sulfonyl](propan-2-yloxy)amino}butanamide

E40, (2R)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-2-{[(4'-methoxybiphenyl-4-yl)sulfonyl](propan-2-yloxy)amino}butanamide (C28 H29 N3 O8 S, 567.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
E40
Formula
C28 H29 N3 O8 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

E40 in 2 structures; the first of them:

  • 4WZV · Crystal structure of a hydroxamate based inhibitor EN140 in complex with the MMP-9… · E40 A301 · binds GLY186, LEU187, LEU188, ALA189, HIS190, ALA191, LEU222, VAL223 and 16 more
  • 4WZV · Crystal structure of a hydroxamate based inhibitor EN140 in complex with the mmp-9… · E40 A301 · binds GLY186, LEU187, LEU188, ALA189, HIS190, ALA191, LEU222, VAL223 and 16 more

Residues it binds most

LEU 4, HIS 4, ALA 4, TYR 4, MET 4, PRO 4, ASP 4, GLU 4, GLY 4, VAL 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • NA · Sodium ion
  • ZN · Zinc ion
  • AZI · Azide ion
  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether
  • PGO · S-1,2-propanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.